Ethanone, 2-hydroxy-1-(2-thienyl)-

Base Information

Chemical Name:Ethanone, 2-hydroxy-1-(2-thienyl)-
CAS No.:88511-88-0
Molecular Formula:C6H6O2S
Molecular Weight:142.178
Hs Code.:
DSSTox Substance ID:DTXSID40574957
Nikkaji Number:J2.249.249G
Wikidata:Q82464159

Synonyms:88511-88-0;2-Hydroxy-1-(2-thienyl)ethanone;Ethanone, 2-hydroxy-1-(2-thienyl)-;2-Hydroxy-1-(thiophen-2-yl)ethan-1-one;2-hydroxy-1-thiophen-2-ylethanone;2-hydroxy-1-(thiophen-2-yl)ethanone;SCHEMBL23855456;DTXSID40574957;AC7083;MFCD16165846;AKOS011306085;SY131036;CS-0458469;A916004

Suppliers and Price of Ethanone, 2-hydroxy-1-(2-thienyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethanone, 2-hydroxy-1-(2-thienyl)-

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:142.00885060
Heavy Atom Count:9
Complexity:114

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CSC(=C1)C(=O)CO

Technology Process of Ethanone, 2-hydroxy-1-(2-thienyl)-

There total 1 articles about Ethanone, 2-hydroxy-1-(2-thienyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 62889-07-0
trimethyl((1-(thiophen-2-yl)vinyl)oxy)silane

: 88511-88-0
2-hydroxy-1-(thiophen-2-yl)ethan-1-one

: 13669-05-1
1,4-bis(thiophen-2-yl)butane-1,4-dione

Guidance literature:: With iodosylbenzene; boron trifluoride diethyl etherate; In water; 0-5 deg C, 2 h then r.t., 2 days;

Reference yield: 93.0%

: 88511-88-0
2-hydroxy-1-(thiophen-2-yl)ethan-1-one

: 85217-69-2,87802-71-9
cinnamyl methyl carbonate

: (2S,3R)-2-hydroxy-3-phenyl-1-(thiophen-2-yl)pent-4-en-1-one

Guidance literature:: With propylamine; bis(1,5-cyclooctadiene)diiridium(I) dichloride; (R,R)-(-)-2,6-bis[2-(hydroxyldiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenole; diethylzinc; (3,5-Dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-((R)-1-phenyl-ethyl)-amine; In tetrahydrofuran; toluene; at 25 - 50 ℃; for 12h; Inert atmosphere; Molecular sieve;

Reference yield: 93.0%

: 88511-88-0
2-hydroxy-1-(thiophen-2-yl)ethan-1-one

: 85217-69-2,87802-71-9
cinnamyl methyl carbonate

: (2S,3R)-2-hydroxy-3-phenyl-1-(thiophen-2-yl)pent-4-en-1-one

: 2-hydroxy-3-phenyl-1-(thiophen-2-yl)pent-4-en-1-one

Guidance literature:: With propylamine; bis(1,5-cyclooctadiene)diiridium(I) dichloride; (R,R)-(-)-2,6-bis[2-(hydroxyldiphenylmethyl)-1-pyrrolidinyl-methyl]-4-methylphenole; diethylzinc; (3,5-Dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-((R)-1-phenyl-ethyl)-amine; In tetrahydrofuran; hexane; toluene; at 20 ℃; for 12h; stereoselective reaction; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1021/jacs.6b06156