(1E)-N~2~-hydroxy-N~1~-(4-methoxyphenyl)-1-nitrosoprop-1-ene-1,2-diamine

Base Information

• Chemical Name: (1E)-N~2~-hydroxy-N~1~-(4-methoxyphenyl)-1-nitrosoprop-1-ene-1,2-diamine
• CAS No.: 26227-40-7
• Molecular Formula: C₁₀H₁₃N₃O₃
• Molecular Weight: 223.232
• Mol file: 26227-40-7.mol

Synonyms:p-Pyruvanisidide,dioxime (8CI)

Chemical Property of (1E)-N~2~-hydroxy-N~1~-(4-methoxyphenyl)-1-nitrosoprop-1-ene-1,2-diamine

Chemical Property:

• Vapor Pressure: 3.94E-06mmHg at 25°C
• Boiling Point: 370.1°Cat760mmHg
• Flash Point: 177.6°C
• Density: 1.25g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1E)-N~2~-hydroxy-N~1~-(4-methoxyphenyl)-1-nitrosoprop-1-ene-1,2-diamine

There total 1 articles about (1E)-N~2~-hydroxy-N~1~-(4-methoxyphenyl)-1-nitrosoprop-1-ene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ α-p-Methoxyphenylamino-α-isonitrosoacetone oxime (26227-40-7)

Guidance literature:

IV, NH2OH*HCl;

Reference yield: 65.0%

nickel(II) chloride hexahydrate + α-p-Methoxyphenylamino-α-isonitrosoacetone oxime (26227-40-7) → trans-bis(4-methoxyphenylaminomethylglyoximato)nickel(II)

Guidance literature:

With KOH; In ethanol; 0.5 equiv. of metal salt in abs. EtOH was added to oxime-compd. soln. inabs. EtOH, stirring for 3-4 h at room temp., pH was adjusted to 5-5.5 w ith 1 % aq. KOH, stirring in water bath at 40-50 °C for 1 h; ppt. was filtered off, washed with EtOH and Et2O, dried in vac. at room temp., elem. anal.;

DOI:10.1081/SIM-100104785

Reference yield: 48.0%

cobalt(II) chloride hexahydrate + α-p-Methoxyphenylamino-α-isonitrosoacetone oxime (26227-40-7) → bis(4-methoxyphenylaminomethylglyoximato)diaquocobalt(II)

Guidance literature:

With KOH; In ethanol; 0.5 equiv. of metal salt in abs. EtOH was added to oxime-compd. soln. inabs. EtOH, stirring for 3-4 h at room temp., pH was adjusted to 5-5.5 w ith 1 % aq. KOH, stirring in water bath at 40-50 °C for 1 h; ppt. was filtered off, washed with EtOH and Et2O, dried in vac. at room temp., elem. anal.;

DOI:10.1081/SIM-100104785