2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide

Base Information

Chemical Name:2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide
CAS No.:88522-37-6
Molecular Formula:C17H16Cl2N2O4S
Molecular Weight:415.297
Hs Code.:
DSSTox Substance ID:DTXSID10530787
Wikidata:Q82402141

Synonyms:88522-37-6;DTXSID10530787;2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide;AKOS003960322

Suppliers and Price of 2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:414.0207836
Heavy Atom Count:26
Complexity:584

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C(=O)C2=CC=C(C=C2)NS(=O)(=O)C3=C(C=CC(=C3)Cl)Cl

Technology Process of 2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide

There total 2 articles about 2,5-Dichloro-N-[4-(morpholine-4-carbonyl)phenyl]benzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 110-91-8,99108-56-2
morpholine

: 88522-31-0
4-(2,5-Dichloro-benzenesulfonylamino)-benzoic acid

: 88522-37-6
2,5-Dichloro-N-[4-(morpholine-4-carbonyl)-phenyl]-benzenesulfonamide

Guidance literature:: With phosphorus trichloride; In toluene; at 120 - 130 ℃; for 3h;

Reference yield:

: 5402-73-3
2,5-dichlorobenzenesulphonyl chloride

: 88522-37-6
2,5-Dichloro-N-[4-(morpholine-4-carbonyl)-phenyl]-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent

2: 61 percent / PCl₃ / toluene / 3 h / 120 - 130 °C

With phosphorus trichloride; In toluene;