2-(biphenyl-4-yl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(biphenyl-4-yl)-5-(4-methylphenyl)-1,3,4-oxadiazole
CAS No.:16112-27-9
Molecular Formula:C21H16 N2 O
Molecular Weight:312.3645
Hs Code.:

Synonyms:1,3,4-Oxadiazole,2-(4-biphenylyl)-5-p-tolyl- (8CI);2-(4-Biphenylyl)-5-(4-methylphenyl)-1,3,4-oxadiazole; mPBD

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(biphenyl-4-yl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Chemical Property:

Vapor Pressure:3.16E-09mmHg at 25°C
Boiling Point:488.8°Cat760mmHg
Flash Point:243.1°C
Density:1.153g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(biphenyl-4-yl)-5-(4-methylphenyl)-1,3,4-oxadiazole

There total 3 articles about 2-(biphenyl-4-yl)-5-(4-methylphenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-85-8
para-methylbenzonitrile

: 16112-27-9
2-(4-biphenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / NaN₃; ZnCl₂ / H₂O / 24 h / Heating

2: 14.2 g / pyridine / 48 h / Heating

With pyridine; sodium azide; zinc(II) chloride; In water;
DOI:10.1016/j.saa.2006.01.030

Reference yield:

: 92-92-2
biphenyl-4-carboxylic acid

: 16112-27-9
2-(4-biphenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 24 h / Heating

2: 14.2 g / pyridine / 48 h / Heating

With pyridine; thionyl chloride;
DOI:10.1016/j.saa.2006.01.030