Technology Process of 5,7-Dibromo-2-phenyl-1h-indole
There total 7 articles about 5,7-Dibromo-2-phenyl-1h-indole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium fluoride; 5,5'-dimethyl-2,2'-bipyridine; trifluorormethanesulfonic acid; palladium diacetate;
In
tetrahydrofuran; water;
at 80 ℃;
for 48h;
chemoselective reaction;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/acs.joc.7b00148
- Guidance literature:
-
With
4,4'-dimethyl-2,2'-bipyridines; bis(acetylacetonato)palladium(II); toluene-4-sulfonic acid;
In
water;
at 80 ℃;
for 48h;
Inert atmosphere;
Schlenk technique;
DOI:10.1039/c7ob00572e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere
2: sodium tetrachloroaurate(III) dihyrate / ethanol; water / 0.5 h / Reflux; Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium tetrachloroaurate(III) dihyrate; diethylamine;
In
tetrahydrofuran; ethanol; water;
DOI:10.1021/ol401098b
