Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Base Information

Chemical Name:Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate
CAS No.:885500-55-0
Molecular Formula:C10H9ClN2O2
Molecular Weight:224.647
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90701231
Wikidata:Q82632824
Mol file:885500-55-0.mol

Synonyms:885500-55-0;Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate;1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 4-chloro-, ethyl ester;4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid ethyl ester;MFCD15529249;Ethyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate;1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid,4-chloro-,ethyl ester;Ethyl 4-Chloro-7-azaindole-5-carboxylate;SCHEMBL566667;DTXSID90701231;YFJJWKAUSJQWAZ-UHFFFAOYSA-N;AMY24567;BCP14348;CS-B0566;AKOS016002002;PB13664;DS-17731;SY106284;FT-0656617;P11815;A842683;4-CHLORO-7-AZAINDOLE-5-CARBOXYLIC ACID ETHYL ESTER;ethyl 4-chloro-1H-pyrrolo[2,3-b]-pyridine-5-carboxylate

Suppliers and Price of Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95+%
1g
$ 347.00

Crysdot
Ethyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95+%
5g
$ 1040.00

Crysdot
Ethyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95+%
10g
$ 1832.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,ethylester
10g
$ 2153.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,ethylester
5g
$ 1410.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,ethylester
1g
$ 388.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,ethylester
100mg
$ 99.00

ChemScene
1H-Pyrrolo[2,3-b]pyridine-5-carboxylicacid,4-chloro-,ethylester
250mg
$ 146.00

Chemenu
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacidethylester 95%+
250mg
$ 193.00

Chemenu
4-Chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacidethylester 95%+
100mg
$ 130.00

Total 30 raw suppliers

Chemical Property of Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Chemical Property:

PKA:12.07±0.40(Predicted)
PSA：54.98000
Density:1.391±0.06 g/cm3(Predicted)
LogP:2.39300
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:224.0352552
Heavy Atom Count:15
Complexity:250

Purity/Quality:

97% ^*data from raw suppliers

Ethyl4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C2C(=C1Cl)C=CN2

Technology Process of Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

There total 1 articles about Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 885500-55-0
ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 5 °C

1.2: 1 h

2.1: sec.-butyllithium / tetrahydrofuran; cyclohexane; hexane / 1 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -78 °C / Inert atmosphere

2.3: 1 h / 20 °C / Inert atmosphere

With sec.-butyllithium; sodium hydride; In tetrahydrofuran; hexane; cyclohexane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.c15-00036

Reference yield: 95.0%

: 885500-55-0
ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

: (+/-)-cis-4-methyl-1-(phenylmethyl)-piperidin-3-ylamine

: (+/-)-cis-ethyl 4-{[1-benzyl-4-methylpiperidin-3-yl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Guidance literature:: With triethylamine; In 1-methyl-pyrrolidin-2-one; at 180 ℃; for 1h; Microwave irradiation;
DOI:10.1016/j.bmc.2015.05.028