3-CYANO-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY

Base Information

• Chemical Name: 3-CYANO-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY
• CAS No.: 2154-70-3
• Molecular Formula: C9H15 N2 O
• Molecular Weight: 167.23
• Mol file: 2154-70-3.mol

Synonyms:3-Cyano-2,2,5,5-tetramethylpyrrolidine-N-oxyl

Chemical Property of 3-CYANO-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY

Chemical Property:

• Vapor Pressure: 0.00131mmHg at 25°C
• Melting Point: 31-33 °C(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 27.03000
• Density: g/cm³
• LogP: 1.67248
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

3-Cyano-PROXYL ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Cyano-PROXYL is a stable free radical that can be used in the ESR technique as a nitroxide standard:For the estimation of relative concentrations of the spin adducts of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) with ·OH and O2.- radicals.For the determination of free radicals present in an aqueous cigarette tar extract.

Technology Process of 3-CYANO-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY

There total 3 articles about 3-CYANO-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-carbamoyl-2,2,5,5-tetramethylpyrrolidin-1-yloxy (46147-12-0,4399-80-8) → 3-cyano-2,2,5,5-tetramethylpyrrolidine-1-oxyl (2154-70-3)

Guidance literature:

With 1,3,5-trichloro-2,4,6-triazine; In N,N-dimethyl-formamide; at 0 ℃; for 0.666667h;

DOI:10.1002/poc.3392

Reference yield:

3-carbamoyl-2,2,5,5-tetramethyl-1-oxopyrrolidinium perchlorate → 3-cyano-2,2,5,5-tetramethylpyrrolidine-1-oxyl (2154-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. buffer / 20 °C

2: 1,3,5-trichloro-2,4,6-triazine / N,N-dimethyl-formamide / 0.67 h / 0 °C

With 1,3,5-trichloro-2,4,6-triazine; In N,N-dimethyl-formamide;

DOI:10.1002/poc.3392

Reference yield:

→ 3-cyano-2,2,5,5-tetramethylpyrrolidine-1-oxyl (2154-70-3)

Guidance literature:

2,2,5,5-Tetramethyl-3-carbamoyl-pyrrolidin-1-oxyl, Py., Tosylchlorid;

DOI:10.1016/S0040-4020(01)82219-5

upstream raw materials:

3-carbamoyl-2,2,5,5-tetramethylpyrrolidin-1-yloxy

Refernces