4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide

Base Information

Chemical Name:4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide
CAS No.:88584-49-0
Molecular Formula:C9H12FNO2S
Molecular Weight:217.264
Hs Code.:
DSSTox Substance ID:DTXSID00519329
Wikidata:Q82382419

Synonyms:88584-49-0;4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide;DTXSID00519329;EN300-704694

Suppliers and Price of 4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:217.05727796
Heavy Atom Count:14
Complexity:263

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)S(=O)(=O)C1=CC=C(C=C1)CF

Technology Process of 4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide

There total 3 articles about 4-(Fluoromethyl)-N,N-dimethylbenzene-1-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1263276-85-2
N,N-dimethyl-4-(trifluoromethyl)benzene-1-sulfonamide

: 599-69-9
N,N,4-trimethylbenzenesulfonamide

: 4-(difluoromethyl)-N,N-dimethylbenzenesulfonamide

: 88584-49-0
4-(fluoromethyl)-N,N-dimethylbenzenesulfonamide

Guidance literature:: With tetraethylammonium perchlorate; triethylamine; In ethanol; dimethyl sulfoxide; at 20 ℃; for 12h; Electrolysis; Green chemistry;
DOI:10.1039/d1gc00317h

Reference yield: 44.0%

: 71398-36-2
N,N-dimethyl-4-diazomethyl benzenesulfonamide

: 58804-18-5
4-hydroxymethyl-benzenesulfonic acid dimethylamide

: 88584-49-0
4-(fluoromethyl)-N,N-dimethylbenzenesulfonamide

: 88584-53-6
C₁₈H₂₄N₂O₅S₂

Guidance literature:: With tetrafluoroboric acid; In dichloromethane; for 0.166667h;
DOI:10.1055/s-1983-30521

Reference yield:

: 2991-42-6
4-trifluorophenylsulfonyl chloride

: 599-69-9
N,N,4-trimethylbenzenesulfonamide

: 4-(difluoromethyl)-N,N-dimethylbenzenesulfonamide

: 88584-49-0
4-(fluoromethyl)-N,N-dimethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 1 h / 0 - 20 °C

2: triethylamine; tetraethylammonium perchlorate / ethanol; dimethyl sulfoxide / 12 h / 20 °C / Electrolysis; Green chemistry

With tetraethylammonium perchlorate; triethylamine; In tetrahydrofuran; ethanol; dimethyl sulfoxide;
DOI:10.1039/d1gc00317h