Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]-

Base Information

• Chemical Name: Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]-
• CAS No.: 88606-09-1
• Molecular Formula: C18H22O2
• Molecular Weight: 270.371
• DSSTox Substance ID: DTXSID40396297
• Nikkaji Number: J633.306K
• Mol file: 88606-09-1.mol

Synonyms:Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]-;88606-09-1;DTXSID40396297;4-Methyl-4'-tert-butyl(2,2'-methylenebisphenol)

Chemical Property of Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]-

Chemical Property:

• XLogP3: 5.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 270.161979940
• Heavy Atom Count: 20
• Complexity: 307

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)O)CC2=C(C=CC(=C2)C(C)(C)C)O

Technology Process of Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]-

There total 2 articles about Phenol, 4-(1,1-dimethylethyl)-2-[(2-hydroxy-5-methylphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

p-cresol (106-44-5) + 2-Benzotriazol-1-ylmethyl-4-tert-butyl-phenol → 4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol (88606-09-1)

Guidance literature:

With sodium isopropylate; In isopropyl alcohol; for 40h; Heating;

DOI:10.1021/jo00103a009

Reference yield:

6'-bromo-4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol → 4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol (88606-09-1)

Guidance literature:

DOI:10.1021/jo9511197

Reference yield: 24.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol (88606-09-1) → 6,6'-bis(bromomethyl)-4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol (173974-54-4)

Guidance literature:

With hydrogen bromide; In acetic acid; for 16h; Ambient temperature;

DOI:10.1021/jo9511197

upstream raw materials:

p-cresol

Downstream raw materials:

6,6'-bis(bromomethyl)-4-tert-butyl-4'-methyl-2,2'-methanediyldiphenol