4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride

Base Information

Chemical Name:4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride
CAS No.:88708-77-4
Molecular Formula:C10H9ClF3N
Molecular Weight:235.636
Hs Code.:
DSSTox Substance ID:DTXSID20525023

Synonyms:4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride;88708-77-4;DTXSID20525023;NBRMCOYLKVYSNG-DHDCSXOGSA-N

Suppliers and Price of 4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:235.0375615
Heavy Atom Count:15
Complexity:229

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=NCC(F)(F)F)Cl

Technology Process of 4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride

There total 3 articles about 4-Methyl-N-(2,2,2-trifluoroethyl)benzene-1-carboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 88708-71-8
2,2,2-Trifluoro-N-(4-methyl-benzyl)-acetimidoyl chloride

: 88708-77-4
4-Methyl-N-(2,2,2-trifluoro-ethyl)-benzimidoyl chloride

Guidance literature:: In toluene; at 110 ℃; Heating;
DOI:10.1246/cl.1983.1463

Reference yield:

: 88708-68-3
2,2,2-trifluoro-N-(4-methylbenzyl)acetamide

: 88708-77-4
4-Methyl-N-(2,2,2-trifluoro-ethyl)-benzimidoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: PCl₅

2: 49 percent / Et₃N / toluene / Heating

With phosphorus pentachloride; triethylamine; In toluene;