Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate

Base Information

Chemical Name:Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate
CAS No.:88737-34-2
Molecular Formula:C20H16N2O4
Molecular Weight:348.358
Hs Code.:
DSSTox Substance ID:DTXSID90528208
Wikidata:Q82397635

Synonyms:88737-34-2;Ethyl (2-benzoylbenzofuran-3-yl)(cyanomethyl)carbamate;DTXSID90528208;Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate

Suppliers and Price of Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:348.11100700
Heavy Atom Count:26
Complexity:563

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)N(CC#N)C1=C(OC2=CC=CC=C21)C(=O)C3=CC=CC=C3

Technology Process of Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate

There total 1 articles about Ethyl (2-benzoyl-1-benzofuran-3-yl)(cyanomethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 49615-93-2
(3-aminobenzo[b]furan-2-yl)phenylmethanone

: 88737-34-2
2-benzoyl-3-(N-ethoxycarbonyl)cyanomethylaminobenzofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / pyridine / benzene / 2 h / Ambient temperature

2: 1) NaH / 1) DMF, r.t., 1 h, 2) r.t., 2 h

With pyridine; sodium hydride; In benzene;

Reference yield: 62.0%

: 108-24-7
acetic anhydride

: 88737-34-2
2-benzoyl-3-(N-ethoxycarbonyl)cyanomethylaminobenzofuran

: 88737-36-4
3-amino-2-benzoylbenzofuran

Guidance literature:: With hydrogen; nickel; In tetrahydrofuran; at 40 ℃; for 5h; under 3800 Torr;

Reference yield:

: 88737-34-2
2-benzoyl-3-(N-ethoxycarbonyl)cyanomethylaminobenzofuran

: 88737-38-6
5-phenyl-2,3-dihydro-1H-benzofuro<3,2-e><1,4>diazepine

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / H₂ / Raney nickel / tetrahydrofuran / 5 h / 40 °C / 3800 Torr

2: 15percentaq.H₂SO₄ / 8 h / Heating

3: 40percentaq.KOH / ethanol / 1 h / Heating

With potassium hydroxide; sulfuric acid; hydrogen; nickel; In tetrahydrofuran; ethanol;