2-(4-Fluorophenyl)-6-methylquinazoline

Base Information

Chemical Name:2-(4-Fluorophenyl)-6-methylquinazoline
CAS No.:88737-70-6
Molecular Formula:C15H11FN2
Molecular Weight:238.264
Hs Code.:
DSSTox Substance ID:DTXSID30518562
Wikidata:Q82381298

Synonyms:2-(4-Fluorophenyl)-6-methylquinazoline;88737-70-6;DTXSID30518562

Suppliers and Price of 2-(4-Fluorophenyl)-6-methylquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(4-Fluorophenyl)-6-methylquinazoline

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:238.09062652
Heavy Atom Count:18
Complexity:276

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CN=C(N=C2C=C1)C3=CC=C(C=C3)F

Technology Process of 2-(4-Fluorophenyl)-6-methylquinazoline

There total 3 articles about 2-(4-Fluorophenyl)-6-methylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 88737-79-5
N-[1-Dimethylamino-meth-(E)-ylidene]-4-fluoro-N'-p-tolyl-benzamidine

: 88737-70-6
2-(4-Fluorophenyl)-6-methylquinazoline

Guidance literature:: With PPA; at 130 - 140 ℃; for 0.5h;
DOI:10.1016/S0040-4039(00)88339-2

Reference yield: 68.0%

: 7292-73-1
(2RS)-N-(p-fluorophenyl)glycine

: 106-49-0,12221-03-3
p-toluidine

: 67-68-5,8070-53-9
dimethyl sulfoxide

: 88737-70-6
2-(4-Fluorophenyl)-6-methylquinazoline

Guidance literature:: With hydrogen iodide; In water; at 140 ℃; for 18h; Sealed tube;
DOI:10.1039/d1cc00623a

Reference yield:

: 21719-79-9
4-Fluoro-N-p-tolyl-benzamidine

: 88737-70-6
2-(4-Fluorophenyl)-6-methylquinazoline

Guidance literature:: Multi-step reaction with 2 steps

2: 69 percent / polyphosphoric acid / 0.5 h / 130 - 140 °C

With PPA;
DOI:10.1016/S0040-4039(00)88339-2