Benzo[h]quinazoline, 2-phenyl-

Base Information

• Chemical Name: Benzo[h]quinazoline, 2-phenyl-
• CAS No.: 88737-72-8
• Molecular Formula: C18H12N2
• Molecular Weight: 256.307
• DSSTox Substance ID: DTXSID90449767
• Nikkaji Number: J3.264.968H
• Wikidata: Q82269282
• Mol file: 88737-72-8.mol

Synonyms:2-phenylbenzo[h]quinazoline;Benzo[h]quinazoline, 2-phenyl-;2-phenyl-benzo[h]quinazoline;88737-72-8;SCHEMBL15489732;DTXSID90449767

Chemical Property of Benzo[h]quinazoline, 2-phenyl-

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 256.100048391
• Heavy Atom Count: 20
• Complexity: 323

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC=C3C=CC4=CC=CC=C4C3=N2

Technology Process of Benzo[h]quinazoline, 2-phenyl-

There total 9 articles about Benzo[h]quinazoline, 2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (Z)-N'-(naphthalen-1-yl)benzimidamide → 2-phenylbenzo[h]quinazoline (88737-72-8)

Guidance literature:

With boron trifluoride diethyl etherate; oxygen; potassium carbonate; In dimethyl sulfoxide; at 140 ℃; for 24h; Sealed tube;

DOI:10.1039/c6gc02319c

Reference yield: 90.0%

N2-(1-Naphthyl)-benzamidin (607-54-5) + N,N-dimethylformamide diethyl diacetal (1188-33-6) → 2-phenylbenzo[h]quinazoline (88737-72-8)

Guidance literature:

Heating;

DOI:10.1016/S0040-4039(00)88339-2

Reference yield: 89.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-(naphthalen-1-yl)benzimidamide (607-54-5) → 2-phenylbenzo[h]quinazoline (88737-72-8)

Guidance literature:

With boron trifluoride diethyl etherate; oxygen; potassium carbonate; In dimethyl sulfoxide; at 140 ℃; for 24h; Sealed tube;

upstream raw materials:

N²-(1-Naphthyl)-benzamidin

N,N-dimethylformamide diethyl diacetal

triethoxymethylbenzene

2-aminomethylnaphthalen-1-ylamine