1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine

Base Information

Chemical Name:1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS No.:64372-72-1
Molecular Formula:C₁₃H₁₆N₄O₄S
Molecular Weight:324.36
Hs Code.:

Synonyms:1H-Pyrazolo[3,4-d]pyrimidine,4-(2-propenylthio)-1-b-D-ribofuranosyl- (9CI); NSC 268235

Suppliers and Price of 1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine

Chemical Property:

Vapor Pressure:2.82E-15mmHg at 25°C
Boiling Point:600.6°Cat760mmHg
Flash Point:317°C
Density:1.67g/cm³

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine

There total 3 articles about 1-pentofuranosyl-4-(prop-2-en-1-ylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5334-23-6
tisopurine

: 64372-72-1
(2R,3R,4S,5R)-2-(4-Allylsulfanyl-pyrazolo[3,4-d]pyrimidin-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / H₂O / 888 h / 35 °C / purine nucleoside phosphorylase, uridine phosphorylase, K₂HPO₄, NaN₃

2: 1.) Dowex 1-X₈ (HCO₃-form) / 1.) methanol, heating, 2.) 24 deg C, 20 h

With Dowex 1-X₈ (HCO₃-form); In water;
DOI:10.1021/jm00343a007

Reference yield:

: 58-96-8
uridine

: 64372-72-1
(2R,3R,4S,5R)-2-(4-Allylsulfanyl-pyrazolo[3,4-d]pyrimidin-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / H₂O / 888 h / 35 °C / purine nucleoside phosphorylase, uridine phosphorylase, K₂HPO₄, NaN₃

2: 1.) Dowex 1-X₈ (HCO₃-form) / 1.) methanol, heating, 2.) 24 deg C, 20 h

With Dowex 1-X₈ (HCO₃-form); In water;
DOI:10.1021/jm00343a007

Reference yield:

: 54524-71-9
4-mercapto-1-β-D-ribofuranosyl-1H-pyrazolo<3,4-d>pyrimidine

: 106-95-6
allyl bromide

: 64372-72-1
(2R,3R,4S,5R)-2-(4-Allylsulfanyl-pyrazolo[3,4-d]pyrimidin-1-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: With Dowex 1-X₈ (HCO₃-form); Yield given. Multistep reaction; 1.) methanol, heating, 2.) 24 deg C, 20 h;
DOI:10.1021/jm00343a007