Formic acid, nitroso-, phenylmethyl ester

Base Information

• Chemical Name: Formic acid, nitroso-, phenylmethyl ester
• CAS No.: 88818-16-0
• Molecular Formula: C8H7NO3
• Molecular Weight: 165.148
• DSSTox Substance ID: DTXSID70473040
• Nikkaji Number: J1.268.207G
• Wikidata: Q82302216
• Mol file: 88818-16-0.mol

Synonyms:Formic acid, nitroso-, phenylmethyl ester;benzyl nitrosoformate;88818-16-0;SCHEMBL1697461;SCHEMBL6545661;DTXSID70473040

Chemical Property of Formic acid, nitroso-, phenylmethyl ester

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 165.042593085
• Heavy Atom Count: 12
• Complexity: 164

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC(=O)N=O

Technology Process of Formic acid, nitroso-, phenylmethyl ester

There total 1 articles about Formic acid, nitroso-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Benzyl N-hydroxycarbamate (3426-71-9) → benzyl nitrosoformat (88818-16-0)

Guidance literature:

With tetraethylammonium metaperiodate; In dichloromethane; at 0 ℃;

DOI:10.1016/S0040-4020(01)87377-4

Reference yield: 93.0%

ethyl 1,3-cyclohexadiene-1-carboxylate (3725-40-4) + benzyl nitrosoformat (88818-16-0) → ethyl 3-benzyloxycarbonyl-2-oxa-3-azabicyclo<2.2.2>oct-5-ene-1-carboxylate (96657-42-0)

Guidance literature:

In dichloromethane;

DOI:10.1039/c39830001049

Reference yield: 92.0%

C7H11CuO3 + benzyl nitrosoformat (88818-16-0) → ethyl 2-(((benzyloxy)carbonyl)(hydroxy)amino)-2-methyl-3-oxobutanoate (1410791-64-8)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); copper(l) chloride; In methanol; at 20 ℃;

DOI:10.1002/anie.201301282

upstream raw materials:

Benzyl N-hydroxycarbamate

Downstream raw materials:

methyl 3-benzyloxycarbonyl-2-oxa-3,5-diazabicyclo<2.2.2>oct-7-ene-5-carboxylate

(1S,4R)-3-Oxa-2,5-diaza-bicyclo[2.2.2]oct-7-ene-2,5-dicarboxylic acid 2-benzyl ester 5-methyl ester

3-benzyloxycarbonyl-2-oxa-3-azabicyclo<2.2.2>oct-5-ene-1-carbonitrile

ethyl 3-benzyloxycarbonyl-2-oxa-3-azabicyclo<2.2.2>oct-5-ene-1-carboxylate