desacetylnavelbine

Base Information

• Chemical Name: desacetylnavelbine
• CAS No.: 126347-74-8
• Molecular Formula: C₄₃H₅₂N₄O₇
• Molecular Weight: 736.908
• Mol file: 126347-74-8.mol

Synonyms:C'-Norvincaleukoblastine,O4-deacetyl-3',4'-didehydro-4'-deoxy-; Aspidospermidine-3-carboxylic acid,6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3,4-dihydroxy-16-methoxy-1-methyl-,methyl ester, (2b,3b,4b,5a,12b,19a)-; Deacetyl vinorelbine; Desacetylnavelbine (base);O-Deacetylnavelbine

Chemical Property of desacetylnavelbine

Chemical Property:

• Boiling Point: °Cat760mmHg
• PKA: 11.67±0.60(Predicted)
• Flash Point: °C
• PSA: 127.80000
• Density: 1.38g/cm³
• LogP: 4.12360

Purity/Quality:

97% ^*data from raw suppliers

Vinorelbine Related Compound A ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Vinorelbine (V315000).

Technology Process of desacetylnavelbine

There total 1 articles about desacetylnavelbine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

vinorelbine (71486-22-1) → 4-deacetyl-8'-noranhydrovinblastine (126347-74-8)

Guidance literature:

With methanol; sodium carbonate; at 65 ℃; for 336h;

DOI:10.1016/j.bmc.2008.04.025

upstream raw materials:

vinorelbine

Refernces