Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)-

Base Information

Chemical Name:Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)-
CAS No.:65437-20-9
Molecular Formula:C30H27N5O7
Molecular Weight:569.5647
Hs Code.:

Synonyms:

Suppliers and Price of Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-trans-anti-BPDE-N2-dG
25mg
$ 18375.00

Total 2 raw suppliers

Chemical Property of Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)-

Chemical Property:

Boiling Point:978.7°Cat760mmHg
Flash Point:545.7°C
PSA：185.98000
Density:1.85g/cm³
LogP:1.65270

Purity/Quality:

97% ^*data from raw suppliers

(+)-trans-anti-BPDE-N2-dG ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (+)-trans-anti-BPDE-N2-dG is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair. Also, as a common concern due to tobacco smoke, Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)- used to obtain a better understanding of the effects of carcinnogen-DNA adducts.

Technology Process of Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)-

There total 1 articles about Guanosine, 2-deoxy-N-((7R,8S,9R,10S)-7,8,9,10-tetrahydro-7,8,9,trihydroxybenzo(a)pyrene-10-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63323-30-8,55097-80-8,58917-67-2,58917-91-2,60268-85-1,60268-86-2,63323-29-5,63323-31-9,63357-09-5,64397-28-0,64912-49-8,64912-50-1,82111-22-6,111137-80-5,91327-01-4
(+/-)-r-7,t-8-Dihydroxy-t-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

: 65883-37-6,76549-36-5,85202-15-9,85202-16-0
1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-4-((7R,8S,9R)-7,8,9-trihydroxy-7,8,9,10-tetrahydro-benzo[def]chrysen-10-ylamino)-1H-pyrimidin-2-one

: 62624-73-1,62696-74-6,65437-20-9,66113-73-3,66141-82-0,66141-83-1,66183-61-7,76581-92-5,79172-11-5,85026-86-4,85026-87-5,92842-66-5,92842-72-3,97859-83-1,103617-96-5
9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-((7R,8R,9R,10R)-7,8,9-trihydroxy-7,8,9,10-tetrahydro-benzo[def]chrysen-10-ylamino)-1,9-dihydro-purin-6-one

Guidance literature:: Yield given. Multistep reaction. Title compound not separated from byproducts; denatured calf thymus DNA;
DOI:10.1021/jo00001a007