2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate

Base Information

Chemical Name:2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate
CAS No.:88948-57-6
Molecular Formula:C37H48O6S
Molecular Weight:620.83800
Hs Code.:
Mol file:88948-57-6.mol

Synonyms:2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate;

Suppliers and Price of 2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate

Chemical Property:

PSA：87.28000
LogP:9.69640

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate

There total 6 articles about 2H-Pyran-2-Methanol,a-decyltetrahydro-4-[(4-Methylphenyl)sulfonyl]-6-(phenylMethoxy)-,benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 88948-56-5
Benzoic acid (R)-1-[(2S,4R)-4-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyran-2-yl]-undecyl ester

: 100-51-6,185532-71-2
benzyl alcohol

: 88948-57-6
Benzoic acid (R)-1-[(2S,4R)-6-benzyloxy-4-(toluene-4-sulfonyl)-tetrahydro-pyran-2-yl]-undecyl ester

Guidance literature:: With bis(trimethylsilyl)sulphate; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1246/cl.1983.1835

Reference yield:

: 88948-48-5
β-p-tosylpropanal diethyl acetal

: 88948-57-6
Benzoic acid (R)-1-[(2S,4R)-6-benzyloxy-4-(toluene-4-sulfonyl)-tetrahydro-pyran-2-yl]-undecyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / p-TsOH / toluene / 4 h / 120 °C

3: 72 percent / BF₃-Et₂O / CH₂Cl₂ / 1.5 h / 0 °C

4: 81 percent / EtO₂CNNCO₂Et, PH₃P / tetrahydrofuran / 20 h / 20 °C

5: 85 percent / bistrimethylsilyl sulfate / CH₂Cl₂ / 3 h / 20 °C

With bis(trimethylsilyl)sulphate; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1246/cl.1983.1835

Reference yield:

: 88948-54-3
Acetic acid (S)-1-[(2S,4R)-4-(toluene-4-sulfonyl)-3,4-dihydro-2H-pyran-2-yl]-undecyl ester

: 88948-57-6
Benzoic acid (R)-1-[(2S,4R)-6-benzyloxy-4-(toluene-4-sulfonyl)-tetrahydro-pyran-2-yl]-undecyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / EtO₂CNNCO₂Et, PH₃P / tetrahydrofuran / 20 h / 20 °C

2: 85 percent / bistrimethylsilyl sulfate / CH₂Cl₂ / 3 h / 20 °C

With bis(trimethylsilyl)sulphate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane;
DOI:10.1246/cl.1983.1835