3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine

Base Information

Chemical Name:3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine
CAS No.:88953-51-9
Molecular Formula:C20H23NO
Molecular Weight:293.409
Hs Code.:
DSSTox Substance ID:DTXSID20516198

Synonyms:88953-51-9;DTXSID20516198;3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine

Suppliers and Price of 3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:293.177964357
Heavy Atom Count:22
Complexity:352

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(OC2N1CCCC2)(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine

There total 3 articles about 3-Methyl-2,2-diphenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4622-24-6
1-(2-Hydroxy-1-methyl-2,2-diphenylethyl)-2-piperidon

: 510-07-6
Tussukal-Base

: 88953-50-8
1-(1-Methyl-2,2-diphenylethenyl)-2-piperidon

: 88953-51-9
3-Methyl-2,2-diphenyl-hexahydro-oxazolo[3,2-a]pyridine

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -70 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

Reference yield:

: 510-07-6
Tussukal-Base

: 88953-51-9
3-Methyl-2,2-diphenyl-hexahydro-oxazolo[3,2-a]pyridine

Guidance literature:: With trityl tetrafluoroborate; In acetonitrile; for 6h; Yield given; Heating;

Reference yield:

: 4622-24-6
1-(2-Hydroxy-1-methyl-2,2-diphenylethyl)-2-piperidon

: 88953-51-9
3-Methyl-2,2-diphenyl-hexahydro-oxazolo[3,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: diisobuthylaluminiumhydride / toluene; CH₂Cl₂ / 1 h / -70 °C

2: triphenylcarbeniumfluoroborate / acetonitrile / 6 h / Heating

With trityl tetrafluoroborate; diisobutylaluminium hydride; In dichloromethane; toluene; acetonitrile;