2-AMINO-2-BORNANECARBOXYLIC ACID

Base Information

• Chemical Name: 2-AMINO-2-BORNANECARBOXYLIC ACID
• CAS No.: 6266-05-3
• Molecular Formula: C₁₁H₁₉NO₂
• Molecular Weight: 197.277
• Mol file: 6266-05-3.mol

Synonyms:2-Bornanecarboxylicacid, 2-amino- (8CI); NSC 32841

Chemical Property of 2-AMINO-2-BORNANECARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 0.00036mmHg at 25°C
• Melting Point: 278 °C(Solv: water (7732-18-5))
• Boiling Point: 295.8°C at 760 mmHg
• PKA: 2.61±0.60(Predicted)
• Flash Point: 132.7°C
• PSA: 63.32000
• Density: 1.116g/cm³
• LogP: 2.31500

Purity/Quality:

99%min ^*data from raw suppliers

2-Amino-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-2-BORNANECARBOXYLIC ACID

There total 4 articles about 2-AMINO-2-BORNANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ optically inactive 2-amino-1,7,7-trimethyl-norbornane-2-carboxylic acid (6266-05-3)

Guidance literature:

With sodium hydroxide;

DOI:10.1007/s004100000214

Reference yield:

(4S,1'R)-1',7',7'-trimethyl-spiro[imidazolidine-4,2'-norbornane]-2,5-dione (17138-06-6) → (1R)-2-amino-1,7,7-trimethyl-norbornane-2exo-carboxylic acid (6266-05-3,17138-08-8,88980-21-6,88980-22-7)

Guidance literature:

With sodium hydroxide;

DOI:10.1007/s004100000214

Reference yield:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (464-49-3,68546-28-1) → (1R)-2-amino-1,7,7-trimethyl-norbornane-2exo-carboxylic acid (6266-05-3,17138-08-8,88980-21-6,88980-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NaCN; 4>2CO₃ / unter Druck

2: aqueous NaOH

With sodium hydroxide; sodium cyanide; ammonium carbonate;

DOI:10.1007/s004100000214

upstream raw materials:

(4S,1'R)-1',7',7'-trimethyl-spiro[imidazolidine-4,2'-norbornane]-2,5-dione

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Downstream raw materials:

3,3-dimethyl-2-methylene-norbornane-1-carboxylic acid