Azacyclododecan-2-one

Base Information

Chemical Name:Azacyclododecan-2-one
CAS No.:1202-71-7
Molecular Formula:C11H21NO
Molecular Weight:183.294
Hs Code.:2933790090
DSSTox Substance ID:DTXSID70501418
Nikkaji Number:J13.165B
Mol file:1202-71-7.mol

Synonyms:Azacyclododecan-2-one;1202-71-7;1-AZACYCLODODECAN-2-ONE;undecalactam;Undecyclolactam;SCHEMBL249693;SCHEMBL16417238;DTXSID70501418;BAA20271;AKOS016344579;6-Isopropyl-5-methylthiomorpholin-3-one;AS-57444;BB 0262704;CS-0196563

Suppliers and Price of Azacyclododecan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Azacyclododecan-2-one

Chemical Property:

Boiling Point:302.517 °C at 760 mmHg
Flash Point:178.798 °C
PSA：32.59000
Density:0.892 g/cm³
LogP:2.90300
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:183.162314293
Heavy Atom Count:13
Complexity:145

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCCCCNC(=O)CCCC1
General Description 1-Azacyclododecan-2-one, also known as undecylolactam or undecanolactam, is a 12-membered lactam that can be synthesized more efficiently in aqueous solutions using cavitand templates, which enhance cyclization by promoting folded conformations of ω-amino acids. This approach improves yields significantly compared to traditional methods, demonstrating the potential for facilitating medium-sized lactam formation in water despite the inherent challenges of ring strain and competing intermolecular reactions. The use of cavitands represents a promising strategy for conducting dehydration-involved organic reactions in aqueous environments.

Technology Process of Azacyclododecan-2-one

There total 21 articles about Azacyclododecan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 946-89-4
cyclododecanone oxime

: 1202-71-7
azacyclododecan-2-one

Guidance literature:: per-rhenic acid; 3,5-bis-trifluromethylphenylboronic acid; In acetonitrile; at 120 ℃; for 4h; Product distribution / selectivity; Heating / reflux;