2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Base Information

Chemical Name:2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol
CAS No.:88973-01-7
Molecular Formula:C23H29NO
Molecular Weight:335.489
Hs Code.:
DSSTox Substance ID:DTXSID70528302
Wikidata:Q82397795

Synonyms:88973-01-7;2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol;DTXSID70528302

Suppliers and Price of 2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Chemical Property:

XLogP3:6.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:335.224914549
Heavy Atom Count:25
Complexity:436

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C2=CN(C3=CC=CC=C32)C

Technology Process of 2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

There total 3 articles about 2,6-Di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 603-76-9
1-methylindole

: 955-02-2
2,6-di-tert-butyl-4-diazo-2,5-cyclohexadien-1-one

: 88973-01-7
2,6-di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Guidance literature:: With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In 1,2-dichloro-ethane; at 23 ℃; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1002/chem.201800648

Reference yield: 2.5%

: 14386-64-2
2-bromo-1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone

: 100-61-8
N-methylaniline

: 88972-94-5
2,6-Di-tert-butyl-4-(1-methyl-1H-indol-2-yl)-phenol

: 88973-01-7
2,6-di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Guidance literature:: at 150 ℃;
DOI:10.1248/cpb.31.3168

Reference yield:

: 950-58-3
2,6-di-tert-butyl-4-aminophenol

: 88973-01-7
2,6-di-tert-butyl-4-(1-methyl-1H-indol-3-yl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / ethanol; water / 0.17 h / 0 °C / Inert atmosphere; Schlenk technique

1.2: 2.17 h / 0 °C / Inert atmosphere; Schlenk technique

2.1: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]} / 1,2-dichloro-ethane / 23 °C / Inert atmosphere; Schlenk technique; Molecular sieve

With hydrogenchloride; bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In ethanol; water; 1,2-dichloro-ethane;
DOI:10.1002/chem.201800648