2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-

Base Information

Chemical Name:2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-
CAS No.:88991-21-3
Molecular Formula:C9H9NO3S
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID00355986

Synonyms:2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-;88991-21-3;SCHEMBL8656951;DTXSID00355986

Suppliers and Price of 2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:211.03031432
Heavy Atom Count:14
Complexity:275

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(=CC1=CSC=C1)C(=O)O

Technology Process of 2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)-

There total 2 articles about 2-Propenoic acid, 2-(acetylamino)-3-(3-thienyl)-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 89000-97-5
(Z)-2-Methyl-5-oxo-4-(3-thienylmethylene)-4,5-dihydro-1,3-oxazole

: 88991-21-3,154593-39-2
(Z)-2-Acetylamino-3-(3-thienyl)-2-propenoic acid

Guidance literature:: With sodium hydroxide; In methanol; Ambient temperature;
DOI:10.1055/s-1983-30556

Reference yield:

: 498-62-4
3-thiophene carboxaldehyde

: 88991-21-3,154593-39-2
(Z)-2-Acetylamino-3-(3-thienyl)-2-propenoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOAc, Ac₂O / 1.5 h / Heating

2: HCl (gas), H₂O / dioxane

With hydrogenchloride; water; sodium acetate; acetic anhydride; In 1,4-dioxane;
DOI:10.1016/S0957-4166(97)00016-5

Reference yield:

: 88991-21-3,154593-39-2
(Z)-2-Acetylamino-3-(3-thienyl)-2-propenoic acid

: 22574-47-6,152612-27-6
D-2-amino-3-thiophen-3-yl-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, (+)-(S)-PROPRAPHOS rhodium complex / methanol / 25 °C / 760 Torr

2: 6 N HCl / 6 h / Heating

With hydrogenchloride; (+)-(S)-PROPRAPHOS rhodium; hydrogen; In methanol;
DOI:10.1016/S0957-4166(00)80424-3