4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride

Base Information

Chemical Name:4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride
CAS No.:50357-45-4
Molecular Formula:C₁₉H₂₄N₄O₂*2ClH
Molecular Weight:413.347
Hs Code.:
UNII:I0I0257YP1
Mol file:50357-45-4.mol

Synonyms:Pentamidine dihydrochloride;4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride;I0I0257YP1;BENZAMIDINE, 4,4'-(PENTAMETHYLENEDIOXY)DI-, DIHYDROCHLORIDE;UNII-I0I0257YP1;Benzenecarboximidamide, 4,4'-(1,5-pentanediylbis(oxy)bis-, dihydrochloride;[amino-[4-[5-[4-[amino(azaniumylidene)methyl]phenoxy]pentoxy]phenyl]methylidene]azanium;dichloride;BENZENECARBOXIMIDAMIDE, 4,4'-(1,5-PENTANEDIYLBIS(OXY))BIS-, DIHYDROCHLORIDE;PENTAMIDINE DIHYDROCHLORIDE [MI];LS-27567;4,4'-(PENTAMETHYLENEDIOXY)DIBENZAMIDINE DIHYDROCHLORIDE

Suppliers and Price of 4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Pentamidinedihydrochloride 98+%
10mg
$ 46.00

Crysdot
Pentamidinedihydrochloride 98+%
100mg
$ 208.00

Crysdot
Pentamidinedihydrochloride 98+%
50mg
$ 137.00

ApexBio Technology
Pentamidinedihydrochloride
50mg
$ 73.00

American Custom Chemicals Corporation
4,4'-(PENTAMETHYLENEDIOXY)DI-BENZAMIDINE DIHYDROCHLORIDE 95.00%
5MG
$ 500.39

Total 12 raw suppliers

Chemical Property of 4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride

Chemical Property:

Vapor Pressure:1.06E-11mmHg at 25°C
Melting Point:232-234°
Boiling Point:539.4°Cat760mmHg
Flash Point:280°C
PSA：118.20000
Density:g/cm³
LogP:5.28490
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:412.1432815
Heavy Atom Count:27
Complexity:365

Purity/Quality:

97% ^*data from raw suppliers

Pentamidinedihydrochloride 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=[NH2+])N)OCCCCCOC2=CC=C(C=C2)C(=[NH2+])N.[Cl-].[Cl-]

Technology Process of 4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride

There total 3 articles about 4,4'-Diamidino-1,5-diphenoxypentane dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 7467-71-2
4,4′-(pentane-1,5-diylbis(oxy))dibenzonitrile

: 50357-45-4,132360-79-3
Pentamidine hydrochloride

Guidance literature:: 4-{[5-(4-cyanophenoxy)pentyl]oxy}benzonitrile; With hydrogenchloride; ethanol; In 1,4-dioxane; at 0 - 20 ℃;

With ammonia; In ethanol; at 20 ℃; for 48h;
DOI:10.1021/jm801547t

Reference yield:

: 619-57-8
p-hydroxybenzamide

: 50357-45-4,132360-79-3
Pentamidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / K₂CO₃ / dimethylformamide / 1 h / Heating

2: 1) triethyloxonium tetrafluoroborat; 2) NH₃ (g) / 1) diethylenglycoledimethylether, 2 d; 2) ethanol, 3 d

With ammonia; triethyloxonium fluoroborate; potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 84223-67-6
4,4'-Pentamethylendioxydibenzamid

: 50357-45-4,132360-79-3
Pentamidine hydrochloride

Guidance literature:: With ammonia; triethyloxonium fluoroborate; Yield given. Multistep reaction; 1) diethylenglycoledimethylether, 2 d; 2) ethanol, 3 d;