1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester

Base Information

Chemical Name:1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester
CAS No.:89021-22-7
Molecular Formula:C18H15NO3
Molecular Weight:293.322
Hs Code.:
DSSTox Substance ID:DTXSID20397101
Nikkaji Number:J3.664.625J
Wikidata:Q82198163

Synonyms:1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester;89021-22-7;DTXSID20397101;J3.664.625J;2-Phenyl-3-formylindolizine-1-carboxylic acid ethyl ester

Suppliers and Price of 1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:293.10519334
Heavy Atom Count:22
Complexity:405

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C2C=CC=CN2C(=C1C3=CC=CC=C3)C=O

Technology Process of 1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester

There total 6 articles about 1-Indolizinecarboxylic acid, 3-formyl-2-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 89021-18-1
3-<(Diisopropoxyphosphinyl)hydroxymethyl>-2-phenyl-1-indolizincarbonsaeure-ethylester

: 89021-22-7
3-Formyl-2-phenyl-1-indolizincarbonsaeure-ethylester

Guidance literature:: With sodium hydroxide; water; for 5h;
DOI:10.1016/S0040-4039(00)94151-0

Reference yield: 81.0%

: 14371-10-9
(E)-3-phenylpropenal

: 2739-98-2
ethyl 2-(pyridinyl-2)acetate

: 89021-22-7
3-Formyl-2-phenyl-1-indolizincarbonsaeure-ethylester

Guidance literature:: (E)-3-phenylpropenal; With α,α-diphenyl-2-pyrrolidinemethanol tert-butyldimethylsilyl ether; In toluene; at 20 ℃; for 0.166667h;

ethyl 2-(pyridinyl-2)acetate; In toluene; at 20 ℃; for 24h;

With dmap; [bis(acetoxy)iodo]benzene; 1,3-dimethylimidazolim iodide; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1021/acs.orglett.7b00566

Reference yield:

: 70508-79-1
(E)-3-Oxo-3-phenyl-1-propenyl-phosphonsaeure-diisopropylester

: 89021-22-7
3-Formyl-2-phenyl-1-indolizincarbonsaeure-ethylester

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / 30percent H₂O₂, Na₂CO₃ / methanol; H₂O / 4 h / 20 °C

2: 50 percent / ethanol / 216 h / Heating

3: 89 percent / 0.5N NaOH / 4 h / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; sodium carbonate; In methanol; ethanol; water;