4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one

Base Information

Chemical Name:4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one
CAS No.:89030-29-5
Molecular Formula:C₁₂H₁₂O₂S
Molecular Weight:220.292
Hs Code.:
DSSTox Substance ID:DTXSID30564786
Wikidata:Q82449610

Synonyms:89030-29-5;4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one;DTXSID30564786

Suppliers and Price of 4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.05580079
Heavy Atom Count:15
Complexity:277

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)OCC1)SC2=CC=CC=C2

Technology Process of 4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one

There total 10 articles about 4-Methyl-3-(phenylsulfanyl)-5,6-dihydro-2H-pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 89030-36-4
3-Methyl-2-phenylsulfinyl-5-pentanolide

: 73978-11-7
2-Hydroxy-3-methyl-2-penten-5-olide

: 89030-29-5
3-Methyl-2-(phenylthio)-2-penten-5-olide

Guidance literature:: With trifluoroacetic anhydride; -15 deg C -> r.t., 2-3 d;
DOI:10.1246/cl.1983.1511

Reference yield:

: 89036-08-8
2-(phenylthio)-5-pentanolide

: 89030-29-5
3-Methyl-2-(phenylthio)-2-penten-5-olide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) mCPBA; 2.) trifluoroacetic anhydride / 1.) CH₂Cl₂, 0 deg C, 1 h; 2.) 0 deg C -> r.t., overnight

2: 91 percent / Me₂S / tetrahydrofuran; diethyl ether / 0.5 h / -25 - -17 °C

3: mCPBA / CH₂Cl₂ / -15 °C

4: 52 percent / (CF₃CO)2O / -15 deg C -> r.t., 2-3 d

With dimethylsulfide; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1246/cl.1983.1511

Reference yield:

: 89030-22-8,89036-09-9,135253-12-2,135253-43-9
3-Methyl-2-phenylthio-5-pentanolide

: 89030-29-5
3-Methyl-2-(phenylthio)-2-penten-5-olide

Guidance literature:: Multi-step reaction with 2 steps

1: mCPBA / CH₂Cl₂ / -15 °C

2: 52 percent / (CF₃CO)2O / -15 deg C -> r.t., 2-3 d

With 3-chloro-benzenecarboperoxoic acid; trifluoroacetic anhydride; In dichloromethane;
DOI:10.1246/cl.1983.1511