Dictamnic acid

Base Information

• Chemical Name: Dictamnic acid
• CAS No.: 523-61-5
• Molecular Formula: C11H9NO4
• Molecular Weight: 219.1935
• DSSTox Substance ID: DTXSID20200323
• Nikkaji Number: J156.554K
• Mol file: 523-61-5.mol

Synonyms:Dictamnic acid;523-61-5;4-Methoxy-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid;CCRIS 8426;3-Quinolinecarboxylic acid, 1,2-dihydro-4-methoxy-2-oxo-;SCHEMBL9730724;DTXSID20200323;4-methoxy-2-quinolone-3-carboxylic acid

Chemical Property of Dictamnic acid

Chemical Property:

• Vapor Pressure: 1.3E-09mmHg at 25°C
• Boiling Point: 469.3°C at 760 mmHg
• Flash Point: 237.7°C
• Density: 1.44g/cm³
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 219.05315777
• Heavy Atom Count: 16
• Complexity: 361

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=O)NC2=CC=CC=C21)C(=O)O

Technology Process of Dictamnic acid

There total 11 articles about Dictamnic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methoxy-3-((E)-3-methyl-but-1-enyl)-1H-quinolin-2-one (95687-74-4) → dictamnic acid (523-61-5)

Guidance literature:

With potassium permanganate; In acetone;

DOI:10.1016/S0040-4039(00)86996-8

Reference yield:

2-hydroxy-4-methoxy-quinoline-3-carboxylic acid ethyl ester (79575-01-2) → Dictaminsaeure (523-61-5)

Guidance literature:

With potassium hydroxide;

Reference yield:

2,4-dihydroxy-quinoline-3-carboxylic acid (73776-24-6) → Dictaminsaeure (523-61-5)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol; H₃PO₄

3: aqueous KOH

With potassium hydroxide; ethanol; phosphoric acid;

upstream raw materials:

2-hydroxy-4-methoxy-quinoline-3-carbaldehyde

dictamnine

2-hydroxy-4-methoxy-quinoline-3-carboxylic acid ethyl ester

2,4-dihydroxy-quinoline-3-carboxylic acid