4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one

Base Information

Chemical Name:4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one
CAS No.:89044-91-7
Molecular Formula:C15H22N2O
Molecular Weight:246.352
Hs Code.:
DSSTox Substance ID:DTXSID90516403

Synonyms:89044-91-7;DTXSID90516403;4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one

Suppliers and Price of 4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:246.173213330
Heavy Atom Count:18
Complexity:272

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NCCCN1C(CC1=O)C2=CC=CC=C2

Technology Process of 4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one

There total 4 articles about 4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 88909-09-5
N-(3-chloropropyl)-4-phenylazetidin-2-one

: 75-31-0
isopropylamine

: 89044-91-7
N-(3-isopropylaminopropyl)-4-phenylazetidin-2-one

Guidance literature:: at 45 ℃; for 96h; sealed tube;
DOI:10.1039/c39830000959

Reference yield:

: 5661-55-2
4-phenylazetidin-2-one

: 89044-91-7
N-(3-isopropylaminopropyl)-4-phenylazetidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / KOH, Bu₄NHSO₄ / tetrahydrofuran / 20 °C

2: 85 percent / 96 h / 45 °C / sealed tube

With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran;
DOI:10.1039/c39830000959

Reference yield:

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 89044-91-7
N-(3-isopropylaminopropyl)-4-phenylazetidin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / diethyl ether / 1 h / Ambient temperature

2: 88 percent / 25percent aq. sodium sulfite, 10percent aq. KOH / diethyl ether; CHCl₃ / 1 h

3: 97 percent / tetrabutylammonium hydrogen sulfate, KOH / tetrahydrofuran / 5 h / Ambient temperature

4: 75 percent / 168 h / Ambient temperature

With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; sodium sulfite; In tetrahydrofuran; diethyl ether; chloroform;