Technology Process of Stannane,
trimethyl[1-methylene-7-[(tetrahydro-2H-pyran-2-yl)oxy]heptyl]-
There total 1 articles about Stannane,
trimethyl[1-methylene-7-[(tetrahydro-2H-pyran-2-yl)oxy]heptyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium chloride;
In
tetrahydrofuran; methanol; water;
To a stirred soln. of Me3SnCu*Me2S in THF (Ar, -78°C) was added sequentially a THF soln. of the 1-alkyne and CH3OH. The mixt. was stirred(10 min) and then at -63°C (12 h). Satd. aq. NH4Cl and ether were added; allowed to warm to room temp.; Aq. phase was extd. (ether). The org. exts. were washed (satd. aq. NH4Cl) and dried (MgSO4). Removal of the solvent; flash chromy. on silica gel followed by distillation. (E)-1-trimethylstannyl-1-alkene not isolated, detected by gas-liq. chromy..;
