1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride

Base Information

• Chemical Name: 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride
• CAS No.: 135938-17-9
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.347
• European Community (EC) Number: 634-386-2
• ChEMBL ID: CHEMBL1256727
• Mol file: 135938-17-9.mol

Synonyms:207572-69-8;135938-17-9;SB 203186 hydrochloride;1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride;SB-203186 (hydrochloride);2-(PIPERIDIN-1-YL)ETHYL 1H-INDOLE-3-CARBOXYLATE HYDROCHLORIDE;SB203186;1H-Indole-3-carboxylic acid, 2-(1-piperidinyl)ethyl ester, hydrochloride (1:1);SB 203186 HCl;2-piperidin-1-ylethyl 1H-indole-3-carboxylate;hydrochloride;SB203186 hydrochloride;SR-01000075810;EU-0100347;MLS002153377;CHEMBL1256727;EX-A7791A;LYMBEMCUJNDSBZ-UHFFFAOYSA-N;AKOS024458649;NCGC00093784-01;BS-45850;SMR001230766;HY-101222;CS-0021007;E78034;S 0443;piperidin-1-ylethyl 1h-indole-3-carboxylate HCl;J-006785;SR-01000075810-1;SR-01000075810-3;piperidin-1-ylethyl-1h-indole-3-carboxylate hydrochloride;2-(PIPERIDIN-1-YL)ETHYL1H-INDOLE-3-CARBOXYLATEHYDROCHLORIDE

Chemical Property of 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride

Chemical Property:

• Vapor Pressure: 1.45E-08mmHg at 25°C
• Boiling Point: 457.8°Cat760mmHg
• PKA: 15.44±0.30(Predicted)
• Flash Point: 230.6°C
• PSA: 45.33000
• Density: g/cm³
• LogP: 3.55050
• Storage Temp.: Store at RT
• Solubility.: H2O: 10 mg/mL
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 308.1291556
• Heavy Atom Count: 21
• Complexity: 328

Purity/Quality:

98%Min ^*data from raw suppliers

SB203186hydrochloride ≥99%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)CCOC(=O)C2=CNC3=CC=CC=C32.Cl
• Uses: SB203186 is a potent 5HT4?serotonin receptor antagonist.

Technology Process of 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride

There total 2 articles about 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-piperidinoethanol (3040-44-6) + Indole-3-carbonyl chloride (59496-25-2) → SB 203186 (135938-17-9)

Guidance literature:

Reference yield:

→ SB 203186 (135938-17-9)

Guidance literature:

upstream raw materials:

1-piperidinoethanol

Indole-3-carbonyl chloride