1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one

Base Information

Chemical Name:1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one
CAS No.:89084-30-0
Molecular Formula:C22H19O4P
Molecular Weight:378.364
Hs Code.:
DSSTox Substance ID:DTXSID30527275

Synonyms:89084-30-0;1-(Benzo[d][1,3]dioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one;DTXSID30527275;1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one

Suppliers and Price of 1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:378.10209608
Heavy Atom Count:27
Complexity:543

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1=CC2=C(C=C1)OCO2)P(=O)(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one

There total 4 articles about 1-(2H-1,3-Benzodioxol-5-yl)-2-(diphenylphosphoryl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 6951-08-2
ethyl 1,3-benzodioxole-5-carboxylate

: 1733-57-9
ethydiphenylphosphine oxide

: 89084-30-0
2-diphenylphosphinoyl-1-(3,4-methylenedioxyphenyl)propan-1-one

Guidance literature:: With n-butyllithium;
DOI:10.1016/S0040-4039(00)88420-8

Reference yield:

: 4736-60-1
ethyltriphenylphosphonium iodide

: 89084-30-0
2-diphenylphosphinoyl-1-(3,4-methylenedioxyphenyl)propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / NaOH / H₂O / Heating

2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) THF, -78 deg C -> RT

With sodium hydroxide; n-butyllithium; In water;

Reference yield:

: 94-53-1
Piperonylic acid

: 89084-30-0
2-diphenylphosphinoyl-1-(3,4-methylenedioxyphenyl)propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 83.3 percent / H₂SO₄ / 18 h / Heating

2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) THF, -78 deg C -> RT

With n-butyllithium; sulfuric acid;