ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

Base Information

Chemical Name:ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate
CAS No.:89088-57-3
Molecular Formula:C7H11N3O2
Molecular Weight:169.183
Hs Code.:
DSSTox Substance ID:DTXSID90531914
Wikidata:Q82404124

Synonyms:89088-57-3;ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate;1H-Pyrazole-5-carboxylic acid, 3-amino-1-methyl-, ethyl ester;ETHYL 5-AMINO-2-METHYLPYRAZOLE-3-CARBOXYLATE;SCHEMBL286585;DTXSID90531914;AKOS000308894;AS-77847;CS-0298922;D97197;EN300-230241;ethyl3-amino-1-methyl-1H-pyrazole-5-carboxylate;Ethyl 5-imino-2-methyl-2,5-dihydro-1h-pyrazole-3-carboxylate

Suppliers and Price of ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:169.085126602
Heavy Atom Count:12
Complexity:174

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=NN1C)N

Technology Process of ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

There total 1 articles about ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 128883-79-4
benzyl 3-(2,5-dimethylpyrrol-1-yl)-1-methylpyrazole-5-carboxylate

: 128883-80-7
benzyl 3-amino-1-methylpyrazole-5-carboxylate

: 89088-57-3
ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

Guidance literature:: With potassium hydroxide; hydroxylamine hydrochloride; In ethanol; for 36h; Heating;

Reference yield: 25.0%

: C₁₂H₁₆ClNO₃S

: 89088-57-3
ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

: C₁₉H₂₆N₄O₅S

Guidance literature:: With dmap; In N,N-dimethyl-formamide; at 20 - 60 ℃;

Reference yield:

: 89088-57-3
ethyl 3-amino-1-methyl-1H-pyrazole-5-carboxylate

: 128883-83-0
3-((tert-butoxycarbonyl)amino)-1-methyl-1H-pyrazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: diisopropylethylamine / dimethylformamide

2: 3.24 g / aq. NaOH / ethanol / 1 h / 45 °C

With sodium hydroxide; N-ethyl-N,N-diisopropylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(00)00219-4