1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-

Base Information

Chemical Name:1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-
CAS No.:89091-87-2
Molecular Formula:C21H25O2P
Molecular Weight:340.402
Hs Code.:
DSSTox Substance ID:DTXSID00447456

Synonyms:1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-;89091-87-2;DTXSID00447456

Suppliers and Price of 1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:340.15921703
Heavy Atom Count:24
Complexity:433

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1CCCCC1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)-

There total 3 articles about 1-Propanone, 1-cyclohexyl-2-(diphenylphosphinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 3289-28-9
ethyl cyclohexanecarboxylate

: 1733-57-9
ethydiphenylphosphine oxide

: 89091-87-2
1-cyclohexyl-2-diphenylphosphinoylpropan-1-one

Guidance literature:: With n-butyllithium; tetramethylpiperidine; 1.) -30 deg C, 1 h; 2.) -78 deg C, 2 h;
DOI:10.1016/0040-4039(96)01601-2

Reference yield:

: 4736-60-1
ethyltriphenylphosphonium iodide

: 89091-87-2
1-cyclohexyl-2-diphenylphosphinoylpropan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / NaOH / H₂O / Heating

2: 1.) n-BuLi / 1.) hexane, THF, 0 deg C, 30 min; 2.) -78 deg C -> RT

With sodium hydroxide; n-butyllithium; In water;