4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-
CAS No.:89112-88-9
Molecular Formula:C16H11ClO2
Molecular Weight:270.715
Hs Code.:
DSSTox Substance ID:DTXSID00351004
Wikidata:Q82127091
Metabolomics Workbench ID:74470
ChEMBL ID:CHEMBL2234619

Synonyms:89112-88-9;2'-Chloro-6-methylflavone;2-(2-Chlorophenyl)-6-methyl-4H-chromen-4-one;4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-;CHEMBL2234619;DTXSID00351004;AKOS002387498;SR-01000394885;SR-01000394885-1

Suppliers and Price of 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:270.0447573
Heavy Atom Count:19
Complexity:390

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3Cl

Technology Process of 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl-

There total 4 articles about 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-6-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 106551-40-0
1-(2-hydroxy-5-methylphenyl)-3-(2-chlorophenyl)propane-1,3-dione

: 89112-88-9
2-(2-chlorophenyl)-6-methyl-4H-chromen-4-one

Guidance literature:: With sodium acetate; acetic acid; for 12h; Reflux;
DOI:10.1007/s00044-011-9701-6

Reference yield:

: 106-44-5
p-cresol

: 89112-88-9
2-(2-chlorophenyl)-6-methyl-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 0.5 h / 20 °C

2: aluminum (III) chloride / 2 h / 120 - 180 °C

3: potassium carbonate / acetone / 12 h / Reflux

4: sodium acetate; acetic acid / 12 h / Reflux

With aluminum (III) chloride; sulfuric acid; sodium acetate; potassium carbonate; acetic acid; In acetone; 2: |Fries Phenol Ester Rearrangement;
DOI:10.1007/s00044-011-9701-6

Reference yield:

: 609-65-4
o-chlorobenzoyl chloride

: 89112-88-9
2-(2-chlorophenyl)-6-methyl-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 12 h / Reflux

2: sodium acetate; acetic acid / 12 h / Reflux

With sodium acetate; potassium carbonate; acetic acid; In acetone;
DOI:10.1007/s00044-011-9701-6