1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)-

Base Information

• Chemical Name: 1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)-
• CAS No.: 89143-08-8
• Molecular Formula: C14H15NO3
• Molecular Weight: 245.278
• DSSTox Substance ID: DTXSID60367181
• Nikkaji Number: J628.392F
• Wikidata: Q82152848
• Mol file: 89143-08-8.mol

Synonyms:1-(4-butoxyphenyl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)-;N-(p-butoxyphenyl)maleimide;N-(4-Butoxyphenyl)maleimide;89143-08-8;DTXSID60367181;STK006353;AKOS001660519

Chemical Property of 1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)-

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 245.10519334
• Heavy Atom Count: 18
• Complexity: 325

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOC1=CC=C(C=C1)N2C(=O)C=CC2=O

Technology Process of 1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)-

There total 3 articles about 1H-Pyrrole-2,5-dione, 1-(4-butoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-(p-butoxyphenyl)maleamic acid (108087-86-1) → N-(p-n-Butoxyphenyl)maleinimide (89143-08-8)

Guidance literature:

With sodium acetate; acetic anhydride; In N,N-dimethyl-formamide; at 50 - 60 ℃; for 4h;

DOI:10.1023/A:1013872506983

Reference yield: 80.0%

p-(n-butoxy)phenylmaleamic acid (96611-33-5,108087-86-1) → N-(p-n-Butoxyphenyl)maleinimide (89143-08-8)

Guidance literature:

With sodium acetate; acetic anhydride; at 90 ℃; for 2h;

Reference yield:

para-butoxyaniline (4344-55-2) → N-(p-n-Butoxyphenyl)maleinimide (89143-08-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / benzene / 2 h

2: 92 percent / sodium acetate; acetic anhydride / dimethylformamide / 4 h / 50 - 60 °C

With sodium acetate; acetic anhydride; In N,N-dimethyl-formamide; benzene;

DOI:10.1023/A:1013872506983

upstream raw materials:

p-(n-butoxy)phenylmaleamic acid

N-(p-butoxyphenyl)maleamic acid

para-butoxyaniline

Downstream raw materials:

N-(p-n-Butoxyphenyl)-α-pyrrolidinosuccinimide

1-(4-Butoxy-phenyl)-3-piperidin-1-yl-pyrrolidine-2,5-dione

1-(4-Butoxy-phenyl)-3-(4-ethoxy-phenylamino)-pyrrolidine-2,5-dione

N-(p-n-Butoxyphenyl)-α-(p-methoxyanilino)-succinimide