2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole

Base Information

Chemical Name:2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole
CAS No.:89173-89-7
Molecular Formula:C16H13BrN2O2
Molecular Weight:345.195
Hs Code.:
DSSTox Substance ID:DTXSID80517323
Wikidata:Q82379268

Synonyms:89173-89-7;2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole;2-(BROMOMETHYL)-1-METHYL-5-NITRO-3-PHENYLINDOLE;DTXSID80517323;AKOS026751151;1-methyl-2-bromomethyl-3-phenyl-5-nitroindole;2-(bromomethyl)-1-methyl-5-nitro-3-phenyl-1{H}-indole

Suppliers and Price of 2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:344.01604
Heavy Atom Count:21
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CBr)C3=CC=CC=C3

Technology Process of 2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole

There total 3 articles about 2-(Bromomethyl)-1-methyl-5-nitro-3-phenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.1%

: 68285-93-8
1,2-dimethyl-3-phenyl-5-nitroindole

: 89173-89-7
1-methyl-2-bromomethyl-3-phenyl-5-nitroindole

Guidance literature:: With bromine; In 1,2-dichloro-ethane; for 1h; Irradiation;
DOI:10.1007/BF00842836

Reference yield:

: 41018-87-5
2-methyl-3-phenyl-5-nitroindole

: 89173-89-7
1-methyl-2-bromomethyl-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

2: 95.1 percent / Br₂ / 1,2-dichloro-ethane / 1 h / 20 °C / Irradiation

With potassium hydroxide; bromine; In 1,2-dichloro-ethane; acetone;
DOI:10.1007/BF00764177

Reference yield:

: 70063-29-5
benzyl methyl ketone p-nitrophenylhydrazone

: 89173-89-7
1-methyl-2-bromomethyl-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / conc. HCl / acetic acid / 2 h / 80 °C

2: 82 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

3: 95.1 percent / Br₂ / 1,2-dichloro-ethane / 1 h / 20 °C / Irradiation

With hydrogenchloride; potassium hydroxide; bromine; In acetic acid; 1,2-dichloro-ethane; acetone;
DOI:10.1007/BF00764177