2-Bromo-6-propoxypyridine

Base Information

• Chemical Name: 2-Bromo-6-propoxypyridine
• CAS No.: 891842-82-3
• Molecular Formula: C₈H₁₀BrNO
• Molecular Weight: 216.077
• Hs Code.: 2933399090
• Mol file: 891842-82-3.mol

Synonyms:2-bromanyl-6-propoxy-pyridine;

Chemical Property of 2-Bromo-6-propoxypyridine

Chemical Property:

• Boiling Point: 242.8±20.0 °C(Predicted)
• PKA: -0.33±0.12(Predicted)
• PSA: 22.12000
• Density: 1.386±0.06 g/cm3(Predicted)
• LogP: 2.63290
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-6-propoxypyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Bromo-6-propoxypyridine acts as a reagent in the preparation of biaryl compounds that functions as GPR120 agonists.

Technology Process of 2-Bromo-6-propoxypyridine

There total 2 articles about 2-Bromo-6-propoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

→ 2-bromo-6-propoxypyridine (891842-82-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h;

Reference yield:

2,6-Dibromopyridine (626-05-1) → 2-bromo-6-propoxypyridine (891842-82-3)

Guidance literature:

propan-1-ol; With sodium;

2,6-Dibromopyridine; at 90 ℃; for 2h;

upstream raw materials:

2,6-Dibromopyridine

Refernces

• 1、 -. "Heterocyclic compounds as inhibitors of factor VIIa". Page/Page column 75. . Retrieved 2008/06/13.