4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester

Base Information

Chemical Name:4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester
CAS No.:89224-54-4
Molecular Formula:C20H17NO5
Molecular Weight:351.359
Hs Code.:

Synonyms:3,7-dimethoxy-4-phenyl-4H-furo[3,2-b]indole-2-carboxylic acid methyl ester;

Suppliers and Price of 4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester

Chemical Property:

PSA：62.83000
LogP:4.18050

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester

There total 9 articles about 4H-Furo[3,2-b]indole-2-carboxylic acid, 3,7-dimethoxy-4-phenyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 89224-53-3
3-hydroxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

: 89224-54-4
3,7-dimethoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

Guidance literature:: With potassium carbonate; dimethyl sulfate; In acetone;

Reference yield: 80.0%

: 93424-83-0
3-hydroxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

: 77-78-1
dimethyl sulfate

: 93424-86-3
3,4-dihydro-7-methoxy-2-methyl-3-oxo-4-phenyl-2H-furo<3,2-b>indole-2-carboxylic acid methyl ester

: 89224-54-4
3,7-dimethoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

Guidance literature:: With potassium carbonate; In acetone; for 48h; Heating;

Reference yield:

: 89224-95-3
5-methoxy-2-(phenylamino)benzoic acid

: 89224-54-4
3,7-dimethoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 83 percent / H₂O; ethanol / 1.25 h / 100 °C

2: 96 percent / H₂O / 2 h / 35 - 40 °C

3: 78 percent / 25percent NaOH / H₂O / 2 h / Heating

4: 1.) 25percent aq. NaOH / 1.) DMF, room temp., 30 min; 2.) room temp., 3 h, 50 - 55 deg C, 30 min

5: 82 percent / sodium methoxide / methanol / 1.5 h / Heating

6: potassium carbonate / acetone / 24 h / Heating

7: 74 percent / potassium t-butoxide / tetrahydrofuran / 18 h

8: 80 percent / potassium carbonate / acetone / 48 h / Heating

With sodium hydroxide; potassium tert-butylate; sodium methylate; potassium carbonate; In tetrahydrofuran; methanol; ethanol; water; acetone;