3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid

Base Information

Chemical Name:3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid
CAS No.:89224-69-1
Molecular Formula:C20H17NO5
Molecular Weight:351.359
Hs Code.:
ChEMBL ID:CHEMBL298056
DSSTox Substance ID:DTXSID50529332

Synonyms:89224-69-1;3-ETHOXY-7-METHOXY-4-PHENYL-4H-FURO[3,2-B]INDOLE-2-CARBOXYLIC ACID;CHEMBL298056;SCHEMBL10654988;DTXSID50529332

Suppliers and Price of 3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:351.11067264
Heavy Atom Count:26
Complexity:508

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=C(OC2=C1N(C3=C2C=C(C=C3)OC)C4=CC=CC=C4)C(=O)O

Technology Process of 3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid

There total 6 articles about 3-Ethoxy-7-methoxy-4-phenyl-4H-furo[3,2-B]indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89224-57-7
3-ethoxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid methyl ester

: 89224-69-1
3-ethoxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 1.5h; Yield given; Heating;

Reference yield:

: 71711-33-6
3-hydroxy-1-phenyl-1H-indole-2-carboxylic acid methyl ester

: 89224-69-1
3-ethoxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 67 percent / potassium carbonate / acetone / 24 h / Heating

2: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h

3: 36 percent / potassium carbonate / acetone / 48 h / Heating

4: 10percent aqueous NaOH / aq. ethanol / 1.5 h / Heating

With sodium hydroxide; potassium tert-butylate; potassium carbonate; In tetrahydrofuran; ethanol; acetone;

Reference yield:

: 85793-68-6
2-<(carboxymethyl)phenylamino>benzoic acid

: 89224-69-1
3-ethoxy-7-methoxy-4-phenyl-4H-furo<3,2-b>indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: conc. H₂SO₄ / 20 h / Heating

2: 71 percent / sodium methoxide / methanol / 1.5 h / Heating

3: 67 percent / potassium carbonate / acetone / 24 h / Heating

4: 60 percent / potassium t-butoxide / tetrahydrofuran / 18 h

5: 36 percent / potassium carbonate / acetone / 48 h / Heating

6: 10percent aqueous NaOH / aq. ethanol / 1.5 h / Heating

With sodium hydroxide; sulfuric acid; potassium tert-butylate; sodium methylate; potassium carbonate; In tetrahydrofuran; methanol; ethanol; acetone;