1-(Pyridin-3-yl)but-3-yn-1-ol

Base Information

Chemical Name:1-(Pyridin-3-yl)but-3-yn-1-ol
CAS No.:89242-75-1
Molecular Formula:C9H9NO
Molecular Weight:147.17400
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50526189
Nikkaji Number:J1.588.246H
Mol file:89242-75-1.mol

Synonyms:1-(Pyridin-3-yl)but-3-yn-1-ol;89242-75-1;1-PYRIDIN-3-YL-BUT-3-YN-1-OL;1-pyridin-3-ylbut-3-yn-1-ol;3-Pyridinemethanol, a-2-propynyl-;SCHEMBL6280604;1-(3-pyridyl)-3-butyn-1-ol;DTXSID50526189;VXYZPCARVIBTEF-UHFFFAOYSA-N;AKOS011516620;SB39670

Suppliers and Price of 1-(Pyridin-3-yl)but-3-yn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-Pyridin-3-yl-but-3-yn-1-ol 97%
500mg
$ 424.00

J&W Pharmlab
1-Pyridin-3-yl-but-3-yn-1-ol 97%
100mg
$ 106.00

Crysdot
1-(Pyridin-3-yl)but-3-yn-1-ol 95+%
1g
$ 581.00

Chemenu
1-Pyridin-3-yl-but-3-yn-1-ol 95%
1g
$ 549.00

Alichem
1-(Pyridin-3-yl)but-3-yn-1-ol
1g
$ 511.92

Total 7 raw suppliers

Chemical Property of 1-(Pyridin-3-yl)but-3-yn-1-ol

Chemical Property:

PSA：33.12000
LogP:1.13830
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:158

Purity/Quality:

95+% ^*data from raw suppliers

1-Pyridin-3-yl-but-3-yn-1-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CCC(C1=CN=CC=C1)O

Technology Process of 1-(Pyridin-3-yl)but-3-yn-1-ol

There total 1 articles about 1-(Pyridin-3-yl)but-3-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 500-22-1
3-pyridinecarboxaldehyde

: 106-96-7
propargyl bromide

: 517907-47-0,517907-64-1
(RS)-1-(3-pyridyl)buta-2,3-dien-1-ol

: 89242-75-1,517907-62-9
(RS)-1-(3-pyridyl)but-3-yn-1-ol

Guidance literature:: With indium; In tetrahydrofuran; water; at 30 ℃; for 16h;
DOI:10.1016/S0957-4166(02)00743-7

Reference yield: 44.0%

: 108-05-4,9003-20-7
vinyl acetate

: 89242-75-1,517907-62-9
(RS)-1-(3-pyridyl)but-3-yn-1-ol

: 517907-62-9
(R)-1-(3-pyridyl)but-3-yn-1-ol

: 517907-62-9
(S)-1-(3-pyridyl)but-3-yn-1-ol

: 517907-54-9
(R)-1-(3-pyridyl)but-3-yn-1-yl acetate

Guidance literature:: With Pseudomonas cepacia lipase immobilized on modified ceramic; In tetrahydrofuran; at 24 ℃; for 28h; Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(02)00743-7

Reference yield:

: 89242-75-1,517907-62-9
(RS)-1-(3-pyridyl)but-3-yn-1-ol

: 517907-62-9
(R)-1-(3-pyridyl)but-3-yn-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / Pseudomonas cepacia lipase immobilized on modified ceramic / tetrahydrofuran / 28 h / 24 °C

2: sodium hydroxide / methanol; H₂O / 20 °C

With sodium hydroxide; Pseudomonas cepacia lipase immobilized on modified ceramic; In tetrahydrofuran; methanol; water;
DOI:10.1016/S0957-4166(02)00743-7