(S)-2-Chlorotryptophan

Base Information

Chemical Name:(S)-2-Chlorotryptophan
CAS No.:89311-53-5
Molecular Formula:C₁₁H₁₁ClN₂O₂
Molecular Weight:238.674
Hs Code.:
Mol file:89311-53-5.mol

Synonyms:(S)-2-Amino-3-(2-chloro-1H-indol-3-yl)-propionic acid;

Suppliers and Price of (S)-2-Chlorotryptophan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of (S)-2-Chlorotryptophan

Chemical Property:

PSA：79.11000
LogP:2.47600

Purity/Quality:: 98% Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-Chlorotryptophan

There total 7 articles about (S)-2-Chlorotryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 808732-41-4
(S)-2-chlorotryptophan methyl ester

: 89311-53-5
2-chloro-L-tryptophan

Guidance literature:: With α-chymotrypsin (type II, from bovine pancreas); sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 6h; Enzymatic reaction;
DOI:10.1021/jacs.7b09000

Reference yield: 76.0%

: 89311-51-3
α-N-(trifluoroacetyl)-2-chloro-L-tryptophan

: 89311-53-5
2-chloro-L-tryptophan

Guidance literature:: With triethylamine; carboxypeptidase A; In water; Ambient temperature;
DOI:10.1021/ja00268a049

Reference yield:

: 1604-49-5
methyl (2S)-3-(1H-indol-3-yl)-2-(trifluoroacetamido)propanoate

: 89311-53-5
2-chloro-L-tryptophan

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / benzoyl peroxide, N-chlorosuccinimide / CCl₄ / 2 h / 40 °C

2: 80 percent / α-chymotrypsin, 1M NaHCO3 / dioxane; H2O / Ambient temperature

3: 76 percent / Et₃N, carboxypeptidase A / H₂O / Ambient temperature

With N-chloro-succinimide; sodium hydrogencarbonate; triethylamine; α-chymotrypsin; carboxypeptidase A; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane; water;
DOI:10.1021/ja00268a049