2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one

Base Information

Chemical Name:2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one
CAS No.:89313-72-4
Molecular Formula:C₁₆H₁₅NO₂
Molecular Weight:253.301
Hs Code.:
DSSTox Substance ID:DTXSID90526067
Wikidata:Q82394206

Synonyms:89313-72-4;2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one;2-(4-ethoxyphenyl)-1-isoindolinone;2-(4-ETHOXYPHENYL)-3H-ISOINDOL-1-ONE;Oprea1_179776;DTXSID90526067;AKOS003623349;AE-848/33816024

Suppliers and Price of 2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:253.110278721
Heavy Atom Count:19
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O

Technology Process of 2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one

There total 3 articles about 2-(4-ethoxyphenyl)-2,3-dihydro-1H-isoindol-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 42473-87-0
2-(4-ethoxyphenyl)isoindoline-1,3-dione

: 89313-72-4
2-(4-ethoxyphenyl)isoindolin-1-one

Guidance literature:: With ethanol; tetrabutylammonium tetrafluoroborate; diisopropylamine; at 20 ℃; for 2.5h; chemoselective reaction; Electrochemical reaction; Schlenk technique; Green chemistry;
DOI:10.1021/acs.orglett.1c00430

Reference yield:

: 156-43-4
4-Ethoxyaniline

: 89313-72-4
2-(4-ethoxyphenyl)isoindolin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 120 °C

2: tetrabutylammonium tetrafluoroborate; diisopropylamine; ethanol / 2.5 h / 20 °C / Electrochemical reaction; Schlenk technique; Green chemistry

With ethanol; tetrabutylammonium tetrafluoroborate; acetic acid; diisopropylamine;
DOI:10.1021/acs.orglett.1c00430

Reference yield:

: 85-44-9
phthalic anhydride

: 89313-72-4
2-(4-ethoxyphenyl)isoindolin-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 120 °C

2: tetrabutylammonium tetrafluoroborate; diisopropylamine; ethanol / 2.5 h / 20 °C / Electrochemical reaction; Schlenk technique; Green chemistry

With ethanol; tetrabutylammonium tetrafluoroborate; acetic acid; diisopropylamine;
DOI:10.1021/acs.orglett.1c00430