7-epi-Brefeldin A

Base Information

Chemical Name:7-epi-Brefeldin A
CAS No.:83710-00-3
Molecular Formula:C₁₆H₂₄O₄
Molecular Weight:280.364
Hs Code.:
UNII:S66RHK02RP
Wikidata:Q105144655

Synonyms:7-epi-Brefeldin;7-epi-Brefeldin A;S66RHK02RP;UNII-S66RHK02RP;NSC-372200;(1R,2E,6S,10E,11aS,13R,14aR)-1,6,7,8,9,11a,12,13,14,14a-Decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent(f)oxacyclotridecin-4-one;4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-, (1R,2E,6S,10E,11aS,13R,14aR)-;83710-00-3

Suppliers and Price of 7-epi-Brefeldin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-epi-Brefeldin A

Chemical Property:

Vapor Pressure:8.99E-12mmHg at 25°C
Boiling Point:492.7°Cat760mmHg
Flash Point:180.8°C
PSA：66.76000
Density:1.108g/cm³
LogP:1.96240
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:280.16745924
Heavy Atom Count:20
Complexity:388

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
Isomeric SMILES:C[C@H]1CCC/C=C/[C@@H]2C[C@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O

Technology Process of 7-epi-Brefeldin A

There total 7 articles about 7-epi-Brefeldin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20350-15-6,62989-97-3,83710-00-3,84277-18-9,88586-99-6,91176-57-7,91176-58-8
Cyanein

Guidance literature:: durch Penicillium simplicissimum;

Reference yield:

: 20350-15-6,62989-97-3,83710-00-3,84277-18-9,88586-99-6,91176-57-7,91176-58-8
4-Epibrefeldin

Guidance literature:: 4-Ketoderivat 5, NaBH4; neben wenig Brefeldin A;
DOI:10.1016/S0040-4039(00)93000-4

Reference yield:

: 73805-74-0,73837-01-1,90383-03-2,90528-75-9
(E)-3-{2-[(2S,4S)-2-((E)-6-Hydroxy-hept-1-enyl)-4-(2-methoxy-ethoxymethoxy)-cyclopentyl]-[1,3]dithian-2-yl}-acrylic acid ethyl ester

: 20350-15-6,62989-97-3,83710-00-3,84277-18-9,88586-99-6,91176-57-7,91176-58-8
Brefeldin A

Guidance literature:: Multi-step reaction with 4 steps

1: 68 percent / Et3N, α-Chlor-N-methylpyridiniumiodid / acetonitrile / 1 h / Heating

2: 83 percent / AgNO₃, N-chlorsuccinimide, lutidine / acetonitrile / 0.03 h / Ambient temperature

3: NaBH₄ / -78 °C

4: TiCl₄

With sodium tetrahydroborate; N-chloro-succinimide; lutidine; 2-chloro-1-methyl-pyridinium iodide; titanium tetrachloride; silver nitrate; triethylamine; In acetonitrile;