Macronecine

Base Information

Chemical Name:Macronecine
CAS No.:21823-73-4
Molecular Formula:C8H15NO2
Molecular Weight:157.2102
Hs Code.:
UNII:XU327N5D2A,D2P2A4GF4J
Nikkaji Number:J15.288I
Mol file:21823-73-4.mol

Synonyms:MACRONECINE;Macronecin;(+)-Macronecine;Macronecine, (+)-;Macronecine, (+/-)-;D2P2A4GF4J;XU327N5D2A;21824-61-3;(1S,2R,7aR)-Hexahydro-2-hydroxy-1H-pyrrolizine-1-methanol;1H-Pyrrolizine-1-methanol, hexahydro-2-hydroxy-, (1S,2R,7aR)-;rel-(1R,2S,7aS)-1-(hydroxymethyl)hexahydro-1H-pyrrolizin-2-ol;rel-(1R,2S,7aS)-Hexahydro-2-hydroxy-1H-pyrrolizine-1-methanol;1H-Pyrrolizine-1-methanol, hexahydro-2-hydroxy-, (1R,2S,7aS)-rel-;1H-Pyrrolizine-1-methanol, hexahydro-2-hydroxy-, [1S-(1alpha,2alpha,7aalpha)]-

Suppliers and Price of Macronecine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Macronecine

Chemical Property:

Vapor Pressure:0.0016mmHg at 25°C
Boiling Point:261.9°Cat760mmHg
Flash Point:131.3°C
Density:1.23g/cm³
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:151

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2C(C(CN2C1)O)CO
Isomeric SMILES:C1C[C@@H]2[C@H]([C@H](CN2C1)O)CO

Technology Process of Macronecine

There total 22 articles about Macronecine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: C₂₄H₃₃NO₂Si

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
rac-(1S,2S,7aR)-1-(hydroxymethyl)hexahydro-1H-pyrrolizin-2-ol

Guidance literature:: C₂₄H₃₃NO₂Si; With hydrogenchloride; methanol; for 1.5h;

With ammonium hydroxide; In water;
DOI:10.1016/j.tet.2009.01.085

Reference yield: 70.0%

: (1R*,2R*,6aR*)-methyl 2-hydroxy-3-oxo-hexahydro-1H-pyrrolizine-1-carboxylate

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
(+/-)-Macronecin

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 17h; Reflux;
DOI:10.1039/C6OB01871H

Reference yield: 62.0%

: C₂₄H₃₃NO₂Si

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
(+/-)-Macronecin

Guidance literature:: C₂₄H₃₃NO₂Si; With hydrogenchloride; methanol; for 1.5h;

With ammonium hydroxide; In water;
DOI:10.1016/j.tet.2009.01.085