2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-

Base Information

Chemical Name:2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-
CAS No.:86818-28-2
Molecular Formula:C₁₇H₁₅NO₃
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID40235839
Wikidata:Q83117742

Synonyms:BRN 4509266;86818-28-2;2-[3-(4-methylphenyl)-2H-1,4-benzoxazin-6-yl]acetic acid;3-p-Tolyl-2H-1,4-benzoxazine-6-acetic acid;2H-1,4-BENZOXAZINE-6-ACETIC ACID, 3-(4-METHYLPHENYL)-;3-(4-Methylphenyl)-2H-1,4-benzoxazine-6-acetic acid;DTXSID40235839;LS-41680

Suppliers and Price of 2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-

Chemical Property:

Vapor Pressure:5.8E-10mmHg at 25°C
Boiling Point:478.4°Cat760mmHg
Flash Point:243.2°C
Density:1.24g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=C(C=CC(=C3)CC(=O)O)OC2

Technology Process of 2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)-

There total 3 articles about 2H-1,4-Benzoxazine-6-acetic acid, 3-(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 86818-22-6
(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-acetic acid ethyl ester

: 86818-28-2
(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-acetic acid

Guidance literature:: With sulfuric acid; Heating;

Reference yield:

: 86818-19-1
Ethyl 3-amino-4-hydroxyphenylacetate

: 86818-28-2
(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / K₂CO₃ / acetone / Heating

2: 70 percent / 20percent H₂SO₄ / Heating

With sulfuric acid; potassium carbonate; In acetone;

Reference yield:

: 619-41-0
4-(bromoacetyl)toluene

: 86818-28-2
(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / K₂CO₃ / acetone / Heating

2: 70 percent / 20percent H₂SO₄ / Heating

With sulfuric acid; potassium carbonate; In acetone;