5-METHOXYNINHYDRIN MONOHYDRATE

Base Information

• Chemical Name: 5-METHOXYNINHYDRIN MONOHYDRATE
• CAS No.: 106507-42-0
• Molecular Formula: C10H8 O5
• Molecular Weight: 208.1675
• Mol file: 106507-42-0.mol

Synonyms:5-Methoxyindane-1,2,3-trionemonohydrate; 5-Methoxyninhydrin

Chemical Property of 5-METHOXYNINHYDRIN MONOHYDRATE

Chemical Property:

• Vapor Pressure: 2.23E-10mmHg at 25°C
• Boiling Point: 489°Cat760mmHg
• Flash Point: 203.2°C
• PSA: 83.83000
• Density: 1.627g/cm³
• LogP: -0.24490

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHOXYNINHYDRIN MONOHYDRATE

There total 6 articles about 5-METHOXYNINHYDRIN MONOHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,2-dibromo-5-methoxy-1,3-indanedione (138485-79-7) → 2,2-dihydroxy-5-methoxyindane-1,3-dione (106507-42-0)

Guidance literature:

With dimethyl sulfoxide; In toluene; at 100 ℃; for 3h;

DOI:10.1080/00397919108055457

Reference yield: 85.0%

5-methoxy-1-indanone (5111-70-6) → 2,2-dihydroxy-5-methoxyindane-1,3-dione (106507-42-0)

Guidance literature:

With selenium(IV) oxide; water; In 1,4-dioxane; at 180 ℃; for 0.0833333h; Sealed tube; Microwave irradiation;

DOI:10.1016/j.tetlet.2015.02.086

Reference yield: 58.0%

3-bromo-6-methoxy-1-indenone (138485-80-0) → 2,2-dihydroxy-5-methoxyindane-1,3-dione (106507-42-0)

Guidance literature:

With bromine; dimethyl sulfoxide; In benzene; for 6h; Heating;

DOI:10.1080/00397919108055457

upstream raw materials:

3-bromo-6-methoxy-1-indenone

2,2-dibromo-5-methoxy-1,3-indanedione

5-Methoxyninhydrin

5-methoxy-1H-indene-1,3(2H)-dione

Downstream raw materials:

7-methoxy-2-[3-(trifluoromethyl)phenyl]-9H-indeno[1,2-c]pyridazin-9-one

Refernces

• 1、 Marminon, Christelle,Nacereddine, Abdelhamid,Bouaziz, Zouhair,Nebois, Pascal,Jose, Joachim,Le Borgne, Marc. "Microwave-assisted oxidation of indan-1-ones into ninhydrins". supporting information. p. 1840 - 1842. Retrieved 2015/03/30.
• 2、 Bowden, Keith,Rumpal, Sanjay. "The Hydration of 1,2,3-Indanetriones and Related Triones". . p. 355 - 374. Retrieved 2007/10/03.