Technology Process of 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione
There total 1 articles about 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium methylate;
Multistep reaction;
1.) dimethylformamid, room temp., 2 h, 2.) dimethylformamid, reflux, 2 h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) CuCl2*2H2O, 2.) NaBH4 / 1.) ethanol, 0 deg C, 1 h , 2.) 0 deg C, 0.5 h
2: 81 percent / HCL aq / 0 °C
3: 70percent aq H3PO4 / 3 h / Heating
4: K2CO3 / dimethylformamide / 3 h / 80 °C
With
hydrogenchloride; sodium tetrahydroborate; phosphoric acid; potassium carbonate;
In
N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) CuCl2*2H2O, 2.) NaBH4 / 1.) ethanol, 0 deg C, 1 h , 2.) 0 deg C, 0.5 h
2: NaBH4 / acetone / -5 - 0 °C
With
sodium tetrahydroborate;
In
acetone;
