4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione

Base Information

Chemical Name:4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione
CAS No.:89508-13-4
Molecular Formula:C17H16N2O3S
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID90521734
Wikidata:Q82386380

Synonyms:89508-13-4;DTXSID90521734;4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione

Suppliers and Price of 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:328.08816355
Heavy Atom Count:23
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C(=O)CN1C(=O)C2=CC=CC=C2)CCC3=CC=CS3

Technology Process of 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione

There total 1 articles about 4-Benzoyl-1-[2-(thiophen-2-yl)ethyl]piperazine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85567-51-7
2-(thiophene-2-yl)ethyl benzenesulfonate

: 78538-74-6
FG 7142

: 89508-13-4
4-Benzoyl-1-(2-thiophen-2-yl-ethyl)-piperazine-2,6-dione

Guidance literature:: With sodium methylate; Multistep reaction; 1.) dimethylformamid, room temp., 2 h, 2.) dimethylformamid, reflux, 2 h;

Reference yield:

: 89508-13-4
4-Benzoyl-1-(2-thiophen-2-yl-ethyl)-piperazine-2,6-dione

: 2-Benzyl-1,2,3,6,7,10b-hexahydro-thieno[3',2':3,4]pyrido[1,2-a]pyrazin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) CuCl₂*2H₂O, 2.) NaBH₄ / 1.) ethanol, 0 deg C, 1 h , 2.) 0 deg C, 0.5 h

2: 81 percent / HCL aq / 0 °C

3: 70percent aq H₃PO₄ / 3 h / Heating

4: K₂CO₃ / dimethylformamide / 3 h / 80 °C

With hydrogenchloride; sodium tetrahydroborate; phosphoric acid; potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 89508-13-4
4-Benzoyl-1-(2-thiophen-2-yl-ethyl)-piperazine-2,6-dione

: N-(2-Hydroxy-ethyl)-N-[(2-thiophen-2-yl-ethylcarbamoyl)-methyl]-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) CuCl₂*2H₂O, 2.) NaBH₄ / 1.) ethanol, 0 deg C, 1 h , 2.) 0 deg C, 0.5 h

2: NaBH₄ / acetone / -5 - 0 °C

With sodium tetrahydroborate; In acetone;