1-(4-Fluorophenyl)hydrazine-1-carbothioamide

Base Information

Chemical Name:1-(4-Fluorophenyl)hydrazine-1-carbothioamide
CAS No.:89521-93-7
Molecular Formula:C7H8FN3S
Molecular Weight:185.225
Hs Code.:
DSSTox Substance ID:DTXSID30523611
Wikidata:Q82389816

Synonyms:89521-93-7;1-(4-Fluorophenyl)hydrazine-1-carbothioamide;SCHEMBL21777201;DTXSID30523611

Suppliers and Price of 1-(4-Fluorophenyl)hydrazine-1-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(4-Fluorophenyl)hydrazine-1-carbothioamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:185.04229660
Heavy Atom Count:12
Complexity:168

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N(C(=S)N)N)F

Technology Process of 1-(4-Fluorophenyl)hydrazine-1-carbothioamide

There total 2 articles about 1-(4-Fluorophenyl)hydrazine-1-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 89521-87-9
1-(4-fluorophenyl)hydrazine-1-carbonitrile

: 89521-93-7
2-(4-fluorophenyl)thiosemicarbazide

Guidance literature:: With hydrogen sulfide; triethylamine; In ethanol; at 5 ℃; ice bath, overnight;

Reference yield:

: 371-14-2
4-fluorophenylhydrazine

: 89521-93-7
2-(4-fluorophenyl)thiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / NaOH / aq. ethanol / 20 h / Ambient temperature

2: 82 percent / hydrogen sulfide, triethylamine / ethanol / 5 °C / ice bath, overnight

With sodium hydroxide; hydrogen sulfide; triethylamine; In ethanol;

Reference yield:

: 89521-93-7
2-(4-fluorophenyl)thiosemicarbazide

: 89522-09-8
1-(4-fluorophenyl)-3-trifluoromethyl-1,2,4-triazole-5(4H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / methanol / 2 h / 66 °C / pH=9

2: 85 percent / tetrahydrofuran / 3 h / Heating

3: 11 percent / sodium hydroxide / methanol; H₂O / 24 h / Heating

With sodium hydroxide; In tetrahydrofuran; methanol; water;