N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine

Base Information

Chemical Name:N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine
CAS No.:89525-53-1
Molecular Formula:C16H18BrNO2
Molecular Weight:336.228
Hs Code.:
DSSTox Substance ID:DTXSID90528364
Nikkaji Number:J2.039.897C
Wikidata:Q82397932

Synonyms:89525-53-1;N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine;DTXSID90528364;AKOS008989808;Z86130307

Suppliers and Price of N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:335.05209
Heavy Atom Count:20
Complexity:271

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)CNCC2=CC=CC=C2)Br)OC

Technology Process of N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine

There total 6 articles about N-Benzyl-1-(2-bromo-4,5-dimethoxyphenyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 100-46-9
benzylamine

: 89525-53-1
1-bromo-2-benzylaminomethyl-4,5-dimethoxybenzene

Guidance literature:: 2-bromo-4,5-dimethoxybenzaldehyde; benzylamine; With acetic acid; In methanol; at 20 ℃; for 0.5h; Inert atmosphere;

With methanol; sodium tetrahydroborate; at 65 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tet.2012.06.106

Reference yield:

: Benzyl-[1-(2-bromo-4,5-dimethoxy-phenyl)-meth-(E)-ylidene]-amine

: 89525-53-1
1-bromo-2-benzylaminomethyl-4,5-dimethoxybenzene

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;
DOI:10.1021/ja038565t

Reference yield:

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 89525-53-1
1-bromo-2-benzylaminomethyl-4,5-dimethoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 0.25 h / Heating

2: 1.82 g / NaBH₄ / methanol / 2 h / 20 °C

With sodium tetrahydroborate; In methanol; toluene;
DOI:10.1021/ja038565t