2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol

Base Information

Chemical Name:2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol
CAS No.:89536-27-6
Molecular Formula:C₁₈H₁₈N₂O₄
Molecular Weight:326.352
Hs Code.:
DSSTox Substance ID:DTXSID90523657
Wikidata:Q82389903

Synonyms:89536-27-6;DTXSID90523657;2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol

Suppliers and Price of 2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:326.12665706
Heavy Atom Count:24
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC(O1)(C2=CC=CC=C2)C3=NC4=CC=CC=C4N3CC(O)O

Technology Process of 2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol

There total 4 articles about 2-[2-(2-Phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl]ethane-1,1-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 89521-85-7
3-<2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl>-1,2-propanediol

: 89536-27-6
2-<2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl>acetaldehyde hydrate

Guidance literature:: With lead(IV) acetate; In benzene; for 0.5h;
DOI:10.1002/jhet.5570200618

Reference yield:

: 955-41-9
2-benzoyl-1H-benzimidazole

: 89536-27-6
2-<2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl>acetaldehyde hydrate

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / p-toluenesulfonic acid / 3 h / 120 °C

2: 59 percent / sodium hydride / dimethylformamide / 15 h / Ambient temperature

3: 65 percent / 10percent sulfuric acid / 3 h / Ambient temperature

4: 50 percent / lead tetraacetate / benzene / 0.5 h

With lead(IV) acetate; sulfuric acid; sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; benzene;
DOI:10.1002/jhet.5570200618

Reference yield:

: 89521-84-6
2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazole

: 89536-27-6
2-<2-(2-phenyl-1,3-dioxolan-2-yl)-1H-benzimidazol-1-yl>acetaldehyde hydrate

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / sodium hydride / dimethylformamide / 15 h / Ambient temperature

2: 65 percent / 10percent sulfuric acid / 3 h / Ambient temperature

3: 50 percent / lead tetraacetate / benzene / 0.5 h

With lead(IV) acetate; sulfuric acid; sodium hydride; In N,N-dimethyl-formamide; benzene;
DOI:10.1002/jhet.5570200618